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Names | |
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IUPAC name
4-Amino-5,6-dihydroxy-5,6-dihydro-2(1H)-pyrimidinone
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Other names
5,6-Dihydroxy-5,6-dihydrocytosine
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Identifiers | |
3D model (
JSmol)
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ChEBI | |
ChemSpider | |
PubChem
CID
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CompTox Dashboard (
EPA)
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Properties | |
C4H7N3O3 | |
Molar mass | 145.118 g·mol−1 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Cytosine glycols are intermediate unstable products of cytosine oxidation. These, in turn, are thought to undergo deamination to uracil glycol, dehydration to 5-hydroxycytosine, or both deamination and dehydration to 5-hydroxyuracil. [1]
The lifetime of cytosine glycols are enhanced in double-stranded DNA compared to the free nucleoside. [2]
![]() | |
Names | |
---|---|
IUPAC name
4-Amino-5,6-dihydroxy-5,6-dihydro-2(1H)-pyrimidinone
| |
Other names
5,6-Dihydroxy-5,6-dihydrocytosine
| |
Identifiers | |
3D model (
JSmol)
|
|
ChEBI | |
ChemSpider | |
PubChem
CID
|
|
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C4H7N3O3 | |
Molar mass | 145.118 g·mol−1 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Cytosine glycols are intermediate unstable products of cytosine oxidation. These, in turn, are thought to undergo deamination to uracil glycol, dehydration to 5-hydroxycytosine, or both deamination and dehydration to 5-hydroxyuracil. [1]
The lifetime of cytosine glycols are enhanced in double-stranded DNA compared to the free nucleoside. [2]