From Wikipedia, the free encyclopedia
V-set and immunoglobulin domain containing 4
Identifiers
SymbolVSIG4
NCBI gene 11326
HGNC 17032
OMIM 300353
RefSeq NM_007268
UniProt Q9Y279
Other data
Locus Chr. X q12-q13.3
Search for
Structures Swiss-model
Domains InterPro

Complement receptor of the immunoglobulin family is a protein expressed in Kupffer cells. [1] It is a critical receptor for the phagocytosis of opsonised particles in the blood. It recognizes iC3b (inactivated C3b) deposited on microbial surfaces.

See also

References

  1. ^ Helmy K, Katschke K, Gorgani N, Kljavin N, Elliott J, Diehl L, Scales S, Ghilardi N, van Lookeren Campagne M (2006). "CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens". Cell. 124 (5): 915–27. doi: 10.1016/j.cell.2005.12.039. PMID  16530040.
From Wikipedia, the free encyclopedia
V-set and immunoglobulin domain containing 4
Identifiers
SymbolVSIG4
NCBI gene 11326
HGNC 17032
OMIM 300353
RefSeq NM_007268
UniProt Q9Y279
Other data
Locus Chr. X q12-q13.3
Search for
Structures Swiss-model
Domains InterPro

Complement receptor of the immunoglobulin family is a protein expressed in Kupffer cells. [1] It is a critical receptor for the phagocytosis of opsonised particles in the blood. It recognizes iC3b (inactivated C3b) deposited on microbial surfaces.

See also

References

  1. ^ Helmy K, Katschke K, Gorgani N, Kljavin N, Elliott J, Diehl L, Scales S, Ghilardi N, van Lookeren Campagne M (2006). "CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens". Cell. 124 (5): 915–27. doi: 10.1016/j.cell.2005.12.039. PMID  16530040.

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