Chaetoxanthones are a class of
chemical compounds which are classified as
xanthones. They have been isolated from marine-derived fungi in the genus Chaetomium.[1] There are four compounds in the class that are designated as chaetoxanthones A through D.[1][2] A laboratory synthesis of (±)-chaetoxanthone B has been reported.[3] The chaetoxanthones are under investigation as potential
antimalarials.[3]
References
^
abPontius, Alexander; Krick, Anja; Kehraus, Stefan; Brun, Reto; König, Gabriele M. (1 September 2008). "Antiprotozoal Activities of Heterocyclic-Substituted Xanthones from the Marine-Derived Fungus Chaetomium sp". Journal of Natural Products. 71 (9): 1579–1584.
doi:
10.1021/np800294q.
PMID18683985.
^Wang, Meng-Hua; Li, Li; Jiang, Tao; Wang, Xue-Wei; Sun, Bin-Da; Song, Bo; Zhang, Qiu-Bo; Jia, Hong-Mei; Ding, Gang; Zou, Zhong-Mei (2015). "Stereochemical determination of tetrahydropyran-substituted xanthones from fungus Chaetomium murorum". Chinese Chemical Letters. 26 (12): 1507–1510.
doi:
10.1016/j.cclet.2015.10.025.
^
abLennon, Amber C.; Tallen, Sara C.; Dabire, Sadiq W.; Quach, Nhu H.; Gladen, Paul T. (October 2021). "Total synthesis of (±)-chaetoxanthone B". Tetrahedron Letters. 82: 153390.
doi:
10.1016/j.tetlet.2021.153390.
S2CID240556659.
Chaetoxanthones are a class of
chemical compounds which are classified as
xanthones. They have been isolated from marine-derived fungi in the genus Chaetomium.[1] There are four compounds in the class that are designated as chaetoxanthones A through D.[1][2] A laboratory synthesis of (±)-chaetoxanthone B has been reported.[3] The chaetoxanthones are under investigation as potential
antimalarials.[3]
References
^
abPontius, Alexander; Krick, Anja; Kehraus, Stefan; Brun, Reto; König, Gabriele M. (1 September 2008). "Antiprotozoal Activities of Heterocyclic-Substituted Xanthones from the Marine-Derived Fungus Chaetomium sp". Journal of Natural Products. 71 (9): 1579–1584.
doi:
10.1021/np800294q.
PMID18683985.
^Wang, Meng-Hua; Li, Li; Jiang, Tao; Wang, Xue-Wei; Sun, Bin-Da; Song, Bo; Zhang, Qiu-Bo; Jia, Hong-Mei; Ding, Gang; Zou, Zhong-Mei (2015). "Stereochemical determination of tetrahydropyran-substituted xanthones from fungus Chaetomium murorum". Chinese Chemical Letters. 26 (12): 1507–1510.
doi:
10.1016/j.cclet.2015.10.025.
^
abLennon, Amber C.; Tallen, Sara C.; Dabire, Sadiq W.; Quach, Nhu H.; Gladen, Paul T. (October 2021). "Total synthesis of (±)-chaetoxanthone B". Tetrahedron Letters. 82: 153390.
doi:
10.1016/j.tetlet.2021.153390.
S2CID240556659.