 | |
| Clinical data | |
|---|---|
| ATC code |
|
| Identifiers | |
| |
| CAS Number | |
| ChEBI | |
| ChEMBL | |
| ECHA InfoCard | 100.164.462 |
| Chemical and physical data | |
| Formula | C10H14O5 |
| Molar mass | 214.217 g·mol−1 |
Cantharidic acid is a selective inhibitor of PP2A ( protein phosphatase 2) and PP1 ( protein phosphatase 1). [1] [2]
It is the hydrolysis product of cantharidin.
See also
References
- ^ "Cantharidic Acid | CAS 28874-45-5".
- ^ Azoulay-Alfaguter I, Strazza M, Peled M, Novak HK, Muller J, Dustin ML, Mor A (August 2017). "The tyrosine phosphatase SHP-1 promotes T cell adhesion by activating the adaptor protein CrkII in the immunological synapse". Science Signaling. 10 (491): eaal2880. doi: 10.1126/scisignal.aal2880. PMC 9437928. PMID 28790195. S2CID 4886031.
 | This pharmacology-related article is a stub. You can help Wikipedia by expanding it. |
|
| |
| Clinical data | |
|---|---|
| ATC code |
|
| Identifiers | |
| |
| CAS Number | |
| ChEBI | |
| ChEMBL | |
| ECHA InfoCard | 100.164.462 |
| Chemical and physical data | |
| Formula | C10H14O5 |
| Molar mass | 214.217 g·mol−1 |
Cantharidic acid is a selective inhibitor of PP2A ( protein phosphatase 2) and PP1 ( protein phosphatase 1). [1] [2]
It is the hydrolysis product of cantharidin.
See also
References
- ^ "Cantharidic Acid | CAS 28874-45-5".
- ^ Azoulay-Alfaguter I, Strazza M, Peled M, Novak HK, Muller J, Dustin ML, Mor A (August 2017). "The tyrosine phosphatase SHP-1 promotes T cell adhesion by activating the adaptor protein CrkII in the immunological synapse". Science Signaling. 10 (491): eaal2880. doi: 10.1126/scisignal.aal2880. PMC 9437928. PMID 28790195. S2CID 4886031.
|
| This pharmacology-related article is a stub. You can help Wikipedia by expanding it. |