Calpurnia may refer to:

Ancient Rome

• Calpurnia gens, an ancient Roman family
  • Calpurnia (wife of Caesar), last wife of Roman dictator Julius Caesar
  • Calpurnia (wife of Pliny), third and last wife of Pliny the Younger and granddaughter of Calpurnius Fabatus
• Lex Acilia Calpurnia (67 BC), a severe law against political corruption
• Lex Calpurnia (149 BC), a law that established a permanent extortion court

Science

• Calpurnia (plant), a genus in the family Fabaceae
• Calpurnia, the central crater in a series of " snowman craters" on the asteroid 4 Vesta
• 2542 Calpurnia, an asteroid

Arts, entertainment, and media

• Calpurnia (band)
• Calpurnia (play), a 2018 play by Audrey Dwyer
• Calpurnia, African-American cook and maid for the Finch family in the novel To Kill a Mockingbird
• Shira Calpurnia, protagonist of three Warhammer 40,000 novels, see List of Warhammer 40,000 novels#Enforcer: Shira Calpurnia
• Calpurnia Virginia Tate, protagonist of the novel The Evolution of Calpurnia Tate

People with the given name

• Calpernia Addams, American transgender author and activist

This disambiguation page lists articles associated with the title Calpurnia.
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