CTRL or Ctrl may refer to several things:

• Channel Tunnel Rail Link or High Speed 1 (HS1), a high-speed railway line linking London with the Channel Tunnel
• Control key, an input button present on most computer keyboards
• CTRL (gene), a gene that in humans encodes the enzyme chymotrypsin-like protease CTRL-1
• Ctrl (web series), an American comedy web series from NBC
• Ctrl (Derek Webb album), a 2012 album by singer-songwriter Derek Webb
• Ctrl (SZA album), a 2017 album by singer-songwriter SZA
• CTRL (TV series), a 2021 Singaporean television drama
• Cyberoam Threat Research Labs, a facility of Cyberoam
• The stock symbol for Control4

• Control-Alt-Delete (disambiguation)
• CNTRL, protein that in humans is encoded by the CNTRL gene
• CNTRL: Beyond EDM, a North American educational initiative, centered on electronic dance music

This disambiguation page lists articles associated with the title CTRL.
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