Casein kinase I isoform epsilon is an
enzyme that in humans is encoded by the CSNK1Egene.[5][6]
Function
The protein encoded by this gene is a
serine/threonine protein kinase and a member of the
casein kinase I protein family, whose members have been implicated in the control of
cytoplasmic and
nuclear processes, including
DNA replication and
repair. The encoded protein is found in the cytoplasm as a monomer and can
phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate proteins of the Period family of
circadian rhythm proteins. A
homolog of this mammalian protein can be found in
Drosophila melanogaster. Known as
doubletime, this protein also plays a role in the phosphorylation of proteins involved in circadian rhythms. Two transcript variants encoding the same protein have been found for this gene.[7]
Casein kinase I isoform epsilon is an
enzyme that in humans is encoded by the CSNK1Egene.[5][6]
Function
The protein encoded by this gene is a
serine/threonine protein kinase and a member of the
casein kinase I protein family, whose members have been implicated in the control of
cytoplasmic and
nuclear processes, including
DNA replication and
repair. The encoded protein is found in the cytoplasm as a monomer and can
phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate proteins of the Period family of
circadian rhythm proteins. A
homolog of this mammalian protein can be found in
Drosophila melanogaster. Known as
doubletime, this protein also plays a role in the phosphorylation of proteins involved in circadian rhythms. Two transcript variants encoding the same protein have been found for this gene.[7]