C-type lectin domain family 1 member B is a
protein that in
humans is encoded by the CLEC1Bgene.[5][6][7]
Natural killer (NK) cells express multiple
calcium-dependent (C-type)
lectin-like
receptors, such as
CD94 (KLRD1; MIM 602894) and
NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I
molecules and either inhibit or activate
cytotoxicity and
cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in
myeloid cells and NK cells.[supplied by OMIM][7]
^Sobanov Y, Bernreiter A, Derdak S, Mechtcheriakova D, Schweighofer B, Duchler M, Kalthoff F, Hofer E (Dec 2001). "A novel cluster of lectin-like receptor genes expressed in monocytic, dendritic and endothelial cells maps close to the NK receptor genes in the human NK gene complex". Eur J Immunol. 31 (12): 3493–503.
doi:
10.1002/1521-4141(200112)31:12<3493::AID-IMMU3493>3.0.CO;2-9.
PMID11745369.
S2CID42415487.
Suzuki-Inoue K, Fuller GL, García A, et al. (2006). "A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2". Blood. 107 (2): 542–9.
doi:
10.1182/blood-2005-05-1994.
PMID16174766.
S2CID168505.
C-type lectin domain family 1 member B is a
protein that in
humans is encoded by the CLEC1Bgene.[5][6][7]
Natural killer (NK) cells express multiple
calcium-dependent (C-type)
lectin-like
receptors, such as
CD94 (KLRD1; MIM 602894) and
NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I
molecules and either inhibit or activate
cytotoxicity and
cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in
myeloid cells and NK cells.[supplied by OMIM][7]
^Sobanov Y, Bernreiter A, Derdak S, Mechtcheriakova D, Schweighofer B, Duchler M, Kalthoff F, Hofer E (Dec 2001). "A novel cluster of lectin-like receptor genes expressed in monocytic, dendritic and endothelial cells maps close to the NK receptor genes in the human NK gene complex". Eur J Immunol. 31 (12): 3493–503.
doi:
10.1002/1521-4141(200112)31:12<3493::AID-IMMU3493>3.0.CO;2-9.
PMID11745369.
S2CID42415487.
Suzuki-Inoue K, Fuller GL, García A, et al. (2006). "A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2". Blood. 107 (2): 542–9.
doi:
10.1182/blood-2005-05-1994.
PMID16174766.
S2CID168505.