Calcyclin-binding protein is a
protein that in humans is encoded by the CACYBPgene.[5][6][7]
The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent
ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.[7]
Sun S, Ning X, Liu J, Liu L, Chen Y, Han S, et al. (May 2007). "Overexpressed CacyBP/SIP leads to the suppression of growth in renal cell carcinoma". Biochemical and Biophysical Research Communications. 356 (4): 864–71.
doi:
10.1016/j.bbrc.2007.03.080.
PMID17400182.
Calcyclin-binding protein is a
protein that in humans is encoded by the CACYBPgene.[5][6][7]
The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent
ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.[7]
Sun S, Ning X, Liu J, Liu L, Chen Y, Han S, et al. (May 2007). "Overexpressed CacyBP/SIP leads to the suppression of growth in renal cell carcinoma". Biochemical and Biophysical Research Communications. 356 (4): 864–71.
doi:
10.1016/j.bbrc.2007.03.080.
PMID17400182.