Small RNAs (sRNAs) have been identified within the C. elegans genome and comparative genomics has shown that they are conserved across several nematode species. These sRNAs contain a characteristic 2,2,7-trimethylguanosine (TMG) cap structure that identifies them as non-coding RNAs that have a functional role within the cell but at present the exact function of these sRNAs is unknown. Immunoprecipitation using antibodies against TMG and RNA microarrays were used to identify these sRNA. [1]
Examples
See also
References
- ^ Jia, D.; Cai, L.; He, H.; Skogerbø, G.; Li, T.; Aftab, N.; Chen, R. (September 2007). "Systematic identification of non-coding RNA 2,2,7-trimethylguanosine cap structures in Caenorhabditis elegans". BMC Molecular Biology. 8: 86. doi: 10.1186/1471-2199-8-86. PMC 2200864. PMID 17903271.
Small RNAs (sRNAs) have been identified within the C. elegans genome and comparative genomics has shown that they are conserved across several nematode species. These sRNAs contain a characteristic 2,2,7-trimethylguanosine (TMG) cap structure that identifies them as non-coding RNAs that have a functional role within the cell but at present the exact function of these sRNAs is unknown. Immunoprecipitation using antibodies against TMG and RNA microarrays were used to identify these sRNA. [1]
Examples
See also
Gallery of C.elegans small RNA secondary structure images | |
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References
- ^ Jia, D.; Cai, L.; He, H.; Skogerbø, G.; Li, T.; Aftab, N.; Chen, R. (September 2007). "Systematic identification of non-coding RNA 2,2,7-trimethylguanosine cap structures in Caenorhabditis elegans". BMC Molecular Biology. 8: 86. doi: 10.1186/1471-2199-8-86. PMC 2200864. PMID 17903271.