Bizarre parosteal osteochondromatous proliferation | |
---|---|
Other names | Nora lesion or Nora disease [1] [2] |
Specialty | Orthopedics |
Symptoms | Painless lump in finger or toe [1] |
Risk factors | Possibly trauma in a minority [1] |
Diagnostic method | Medical imaging [1] |
Differential diagnosis | Mainly subungal exostosis [1] |
Treatment | Surgical excision. [1] |
Prognosis | Up to 50% recur after surgery [1] |
Frequency | Rare, [2] <5% of cartilage tumors, [3] M=F [1] |
Bizarre parosteal osteochondromatous proliferation (BPOP), also known as Nora's lesion, [4] is a type of non-cancerous bone tumor belonging to the group of cartilage tumors. [1] [2] [5] It is generally seen in the tubular bones of the hands and feet, [6] where it presents with a rapidly enlarging painless lump in a finger or toe. [1]
It is composed of bone, cartilage and spindle cells. [1] Some people report previous trauma. [1]
Diagnosis is by medical imaging. [1] Treatment is by surgical excision. [1] Up to 50% recur after surgery. [1]
It is rare, [2] and occurs more often in the 20s and 30s. [1] Combined with subungal exostosis, it accounts for less than 5% of cartilage tumors. [3] Males and females are affected equally. [1] The condition was first described by Frederick E. Nora in 1983. [6] [7]
BPOP generally presents with a 1–3 cm painless lump in a finger or more frequently a toe. [1] Growth can be rapid. [2]
It is composed of bone, cartilage and spindle cells. [1] A small number of people have reported previous trauma. [1]
Medical imaging usually shows a well-defined wide-based bony growth on the surface of bone. [6]
BPOP is distinct from subungal exostosis. [1] [6] Conditions that may appear similar to BPOP include: myositis ossficans, ostechondroma, surface osteosarcoma and granulomatous infection. [2]
Treatment is by surgical excision. [1]
Up to 50% recur after surgery. [1] [2]
BPOP is rare. [2] It is most often seen in people in their 20s and 30s. [1] Combined with subungal exostosis, it accounts for less than 5% of cartilage tumors. [3] Males and females are affected equally. [1] [6]
Bizarre parosteal osteochondromatous proliferation was first described by Frederick E. Nora in 1983. [6] [7] Generally in the US, it has been thought of as a mouthful and hence it is sometimes referred to as Nora's lesion. [4]
In 1998 a report of a similar lesion to BPOP was reported in a wallaby. [8]
Bizarre parosteal osteochondromatous proliferation | |
---|---|
Other names | Nora lesion or Nora disease [1] [2] |
Specialty | Orthopedics |
Symptoms | Painless lump in finger or toe [1] |
Risk factors | Possibly trauma in a minority [1] |
Diagnostic method | Medical imaging [1] |
Differential diagnosis | Mainly subungal exostosis [1] |
Treatment | Surgical excision. [1] |
Prognosis | Up to 50% recur after surgery [1] |
Frequency | Rare, [2] <5% of cartilage tumors, [3] M=F [1] |
Bizarre parosteal osteochondromatous proliferation (BPOP), also known as Nora's lesion, [4] is a type of non-cancerous bone tumor belonging to the group of cartilage tumors. [1] [2] [5] It is generally seen in the tubular bones of the hands and feet, [6] where it presents with a rapidly enlarging painless lump in a finger or toe. [1]
It is composed of bone, cartilage and spindle cells. [1] Some people report previous trauma. [1]
Diagnosis is by medical imaging. [1] Treatment is by surgical excision. [1] Up to 50% recur after surgery. [1]
It is rare, [2] and occurs more often in the 20s and 30s. [1] Combined with subungal exostosis, it accounts for less than 5% of cartilage tumors. [3] Males and females are affected equally. [1] The condition was first described by Frederick E. Nora in 1983. [6] [7]
BPOP generally presents with a 1–3 cm painless lump in a finger or more frequently a toe. [1] Growth can be rapid. [2]
It is composed of bone, cartilage and spindle cells. [1] A small number of people have reported previous trauma. [1]
Medical imaging usually shows a well-defined wide-based bony growth on the surface of bone. [6]
BPOP is distinct from subungal exostosis. [1] [6] Conditions that may appear similar to BPOP include: myositis ossficans, ostechondroma, surface osteosarcoma and granulomatous infection. [2]
Treatment is by surgical excision. [1]
Up to 50% recur after surgery. [1] [2]
BPOP is rare. [2] It is most often seen in people in their 20s and 30s. [1] Combined with subungal exostosis, it accounts for less than 5% of cartilage tumors. [3] Males and females are affected equally. [1] [6]
Bizarre parosteal osteochondromatous proliferation was first described by Frederick E. Nora in 1983. [6] [7] Generally in the US, it has been thought of as a mouthful and hence it is sometimes referred to as Nora's lesion. [4]
In 1998 a report of a similar lesion to BPOP was reported in a wallaby. [8]