| |||
| |||
| |||
| Names | |||
|---|---|---|---|
|
Preferred IUPAC name
1,3-Dichloropropan-2-one | |||
| Other names
1,3-Dichloroacetone
α,α'-Dichloroacetone | |||
| Identifiers | |||
3D model (
JSmol)
|
|||
| ChEMBL | |||
| ChemSpider | |||
| ECHA InfoCard | 100.007.806 | ||
| EC Number |
| ||
PubChem
CID
|
|||
| UNII | |||
| UN number | 2649 | ||
CompTox Dashboard (
EPA)
|
|||
| |||
| |||
| Properties | |||
| C3H4Cl2O | |||
| Molar mass | 126.96 g·mol−1 | ||
| Hazards | |||
| Occupational safety and health (OHS/OSH): | |||
Main hazards
|
Extremely toxic. Dangerous to the skin and eyes | ||
| GHS labelling: | |||
| |||
| Danger | |||
| H300, H310, H314, H330, H341, H410 | |||
| P201, P202, P260, P262, P264, P270, P271, P273, P280, P281, P284, P301+P310, P301+P330+P331, P302+P350, P303+P361+P353, P304+P340, P305+P351+P338, P308+P313, P310, P320, P321, P322, P330, P361, P363, P391, P403+P233, P405, P501 | |||
| NFPA 704 (fire diamond) | |||
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
| |||
Bis(chloromethyl) ketone is a chemical substance with formula C
3H
4Cl
2O. It is a solid, and is used in the making of
citric acid. Exposures such as contact or inhalation of bis(chloromethyl) ketone can result in irritation or damage to
skin,
eyes,
throat,
lungs,
liver and
kidneys, as well as headaches and fainting.
[1] As both chlorine atoms tend to react at the same time, the compound is primarily useful for synthesis of various
ring compounds.
[2]
Legal aspects
Bis(chloromethyl) ketone is a substance which is classified as an extremely hazardous substance in the United States as defined in Section 302 of the U.S. Emergency Planning and Community Right-to-Know Act (42 U.S.C. 11002), and is subject to strict reporting requirements by facilities which produce, store, or use it in significant quantities. [3]
See also
References
- ^ Hazardous Substance Fact Sheet from the New Jersey Department of Health and Senior Services
- ^ DePuy, Charles H.; Pettigrew, Jeremy D. "1,3&x2011;Dichloroacetone". Encyclopedia of Reagents for Organic Synthesis. doi: 10.1002/047084289X.rd083.pub2.
- ^ 40 C.F.R.: Appendix A to Part 355—The List of Extremely Hazardous Substances and Their Threshold Planning Quantities (PDF) (Report) (July 1, 2008 ed.). Government Printing Office. Archived from the original (PDF) on February 25, 2012. Retrieved October 29, 2011.
|
| |||
|
| |||
| |||
| Names | |||
|---|---|---|---|
|
Preferred IUPAC name
1,3-Dichloropropan-2-one | |||
| Other names
1,3-Dichloroacetone
α,α'-Dichloroacetone | |||
| Identifiers | |||
3D model (
JSmol)
|
|||
| ChEMBL | |||
| ChemSpider | |||
| ECHA InfoCard | 100.007.806 | ||
| EC Number |
| ||
PubChem
CID
|
|||
| UNII | |||
| UN number | 2649 | ||
CompTox Dashboard (
EPA)
|
|||
| |||
| |||
| Properties | |||
| C3H4Cl2O | |||
| Molar mass | 126.96 g·mol−1 | ||
| Hazards | |||
| Occupational safety and health (OHS/OSH): | |||
Main hazards
|
Extremely toxic. Dangerous to the skin and eyes | ||
| GHS labelling: | |||
|
| |||
| Danger | |||
| H300, H310, H314, H330, H341, H410 | |||
| P201, P202, P260, P262, P264, P270, P271, P273, P280, P281, P284, P301+P310, P301+P330+P331, P302+P350, P303+P361+P353, P304+P340, P305+P351+P338, P308+P313, P310, P320, P321, P322, P330, P361, P363, P391, P403+P233, P405, P501 | |||
| NFPA 704 (fire diamond) | |||
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
| |||
Bis(chloromethyl) ketone is a chemical substance with formula C
3H
4Cl
2O. It is a solid, and is used in the making of
citric acid. Exposures such as contact or inhalation of bis(chloromethyl) ketone can result in irritation or damage to
skin,
eyes,
throat,
lungs,
liver and
kidneys, as well as headaches and fainting.
[1] As both chlorine atoms tend to react at the same time, the compound is primarily useful for synthesis of various
ring compounds.
[2]
Legal aspects
Bis(chloromethyl) ketone is a substance which is classified as an extremely hazardous substance in the United States as defined in Section 302 of the U.S. Emergency Planning and Community Right-to-Know Act (42 U.S.C. 11002), and is subject to strict reporting requirements by facilities which produce, store, or use it in significant quantities. [3]
See also
References
- ^ Hazardous Substance Fact Sheet from the New Jersey Department of Health and Senior Services
- ^ DePuy, Charles H.; Pettigrew, Jeremy D. "1,3&x2011;Dichloroacetone". Encyclopedia of Reagents for Organic Synthesis. doi: 10.1002/047084289X.rd083.pub2.
- ^ 40 C.F.R.: Appendix A to Part 355—The List of Extremely Hazardous Substances and Their Threshold Planning Quantities (PDF) (Report) (July 1, 2008 ed.). Government Printing Office. Archived from the original (PDF) on February 25, 2012. Retrieved October 29, 2011.