This article may be too technical for most readers to understand.(July 2016) |
Biphenotypic sinonasal sarcoma | |
---|---|
Other names | BSNS, LGSSNMF (archaic name) |
A high-power view of a hematoxylin- and eosin-stained slide showing respiratory epithelial inclusions within a spindled cell neoplasm showing characteristics of a biphenotypic sinonasal sarcoma | |
Specialty | Oncology, ENT surgery |
Symptoms | Various upper respiratory symptoms such as difficulty breathing |
Usual onset | Ages 24-85 (Average of 52 years) |
Diagnostic method | Biopsy |
Differential diagnosis | Synovial sarcoma, fibrosarcoma, and other related sarcomas of the ENT |
Treatment | Surgery with radiation |
Prognosis | Good |
Frequency | Very Rare |
Deaths | 0 |
Biphenotypic sinonasal sarcoma is a newly recognized, very rare, low-grade malignant tumor of the nasal cavity, which was formerly probably included in fibrosarcoma and synovial sarcoma cases. It was incorporated into the fourth edition of the World Health Organization Classification of Head and Neck Tumours, published in 2017. [1]
Abbreviations:
Definitions:
The tumor often affects multiple sites within the upper aerodigestive tract, frequently showing extension into the orbit (25%) or through the cribriform plate (11%) of the ethmoid sinus into the skull base. The patient presents with nonspecific findings, including difficulty breathing, facial pressure, congestion, pain, and mild epiphora. Often, concurrent benign sinonasal tract inflammatory polyps are seen.
As it is newly described, this tumor is probably under-reported, though it is considered to be very rare. Patients present over a wide age range (24–85 years), with a mean age of 52 years. More females are diagnosed than males (2:1).
This article may be too technical for most readers to understand.(July 2016) |
Biphenotypic sinonasal sarcoma | |
---|---|
Other names | BSNS, LGSSNMF (archaic name) |
A high-power view of a hematoxylin- and eosin-stained slide showing respiratory epithelial inclusions within a spindled cell neoplasm showing characteristics of a biphenotypic sinonasal sarcoma | |
Specialty | Oncology, ENT surgery |
Symptoms | Various upper respiratory symptoms such as difficulty breathing |
Usual onset | Ages 24-85 (Average of 52 years) |
Diagnostic method | Biopsy |
Differential diagnosis | Synovial sarcoma, fibrosarcoma, and other related sarcomas of the ENT |
Treatment | Surgery with radiation |
Prognosis | Good |
Frequency | Very Rare |
Deaths | 0 |
Biphenotypic sinonasal sarcoma is a newly recognized, very rare, low-grade malignant tumor of the nasal cavity, which was formerly probably included in fibrosarcoma and synovial sarcoma cases. It was incorporated into the fourth edition of the World Health Organization Classification of Head and Neck Tumours, published in 2017. [1]
Abbreviations:
Definitions:
The tumor often affects multiple sites within the upper aerodigestive tract, frequently showing extension into the orbit (25%) or through the cribriform plate (11%) of the ethmoid sinus into the skull base. The patient presents with nonspecific findings, including difficulty breathing, facial pressure, congestion, pain, and mild epiphora. Often, concurrent benign sinonasal tract inflammatory polyps are seen.
As it is newly described, this tumor is probably under-reported, though it is considered to be very rare. Patients present over a wide age range (24–85 years), with a mean age of 52 years. More females are diagnosed than males (2:1).