Biofabrication is a branch of biotechnology specialising in the research and development of biologically engineered processes for the automated production of biologically functional products through bioprinting or bioassembly and subsequent tissue maturation processes; [1] as well as techniques such as directed assembly, which employs localised external stimuli guide the fabrification process; enzymatic assembly, which utilises selective biocatalysts to build macromolecular structures; and self-assembly, in which the biological material guides its own assembly according to its internal information. [2] These processes may facilitate fabrication at the micro- and nanoscales. [2] Biofabricated products are constructed and structurally organised with a range of biological materials including bioactive molecules, biomaterials, living cells, cell aggregates such as micro- tissues and micro- organs on chips, and hybrid cell-material constructs. [1]
See also
- Biofabrication (journal) – academic journal
- Bionics – Application of natural systems to technology
- Biosensor – Probe which tests for biological molecules
- Organ culture – Cultivation of organ tissue in vitro
- Synthetic biology – Interdisciplinary branch of biology and engineering
- Tissue engineering – Biomedical engineering discipline
- CRISPR gene editing – Gene editing method
References
- ^ a b Moroni et al. (2018).
- ^ a b Yi et al. (2005).
Works cited
- Moroni, Lorenzo; Boland, Thomas; Burdick, Jason A.; De Maria, Carmelo; Derby, Brian; Forgacs, Gabor; Groll, Jürgen; Li, Qing; Malda, Jos; Mironov, Vladimir A.; Mota, Carlos; Nakamura, Makoto; Shu, Wenmiao; Takeuchi, Shoji; Woodfield, Tim B.F. (2018). "Biofabrication: A Guide to Technology and Terminology". Trends in Biotechnology. 36 (4): 384–402. doi: 10.1016/j.tibtech.2017.10.015. hdl: 11568/885392. PMID 29137814. S2CID 3704554.
- Yi, Hyunmin; Wu, Li-Qun; Bentley, William E.; Ghodssi, Reza; Rubloff, Gary W.; Culver, James N.; Payne, Gregory F. (2005). "Biofabrication with Chitosan". Biomacromolecules. 6 (6): 2881–2894. doi: 10.1021/bm050410l. ISSN 1525-7797. PMID 16283704.
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| Biological concepts | |||||
| General concepts | |||||
| Basic techniques and tools |
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 | This article about biological engineering is a stub. You can help Wikipedia by expanding it. |
Biofabrication is a branch of biotechnology specialising in the research and development of biologically engineered processes for the automated production of biologically functional products through bioprinting or bioassembly and subsequent tissue maturation processes; [1] as well as techniques such as directed assembly, which employs localised external stimuli guide the fabrification process; enzymatic assembly, which utilises selective biocatalysts to build macromolecular structures; and self-assembly, in which the biological material guides its own assembly according to its internal information. [2] These processes may facilitate fabrication at the micro- and nanoscales. [2] Biofabricated products are constructed and structurally organised with a range of biological materials including bioactive molecules, biomaterials, living cells, cell aggregates such as micro- tissues and micro- organs on chips, and hybrid cell-material constructs. [1]
See also
- Biofabrication (journal) – academic journal
- Bionics – Application of natural systems to technology
- Biosensor – Probe which tests for biological molecules
- Organ culture – Cultivation of organ tissue in vitro
- Synthetic biology – Interdisciplinary branch of biology and engineering
- Tissue engineering – Biomedical engineering discipline
- CRISPR gene editing – Gene editing method
References
- ^ a b Moroni et al. (2018).
- ^ a b Yi et al. (2005).
Works cited
- Moroni, Lorenzo; Boland, Thomas; Burdick, Jason A.; De Maria, Carmelo; Derby, Brian; Forgacs, Gabor; Groll, Jürgen; Li, Qing; Malda, Jos; Mironov, Vladimir A.; Mota, Carlos; Nakamura, Makoto; Shu, Wenmiao; Takeuchi, Shoji; Woodfield, Tim B.F. (2018). "Biofabrication: A Guide to Technology and Terminology". Trends in Biotechnology. 36 (4): 384–402. doi: 10.1016/j.tibtech.2017.10.015. hdl: 11568/885392. PMID 29137814. S2CID 3704554.
- Yi, Hyunmin; Wu, Li-Qun; Bentley, William E.; Ghodssi, Reza; Rubloff, Gary W.; Culver, James N.; Payne, Gregory F. (2005). "Biofabrication with Chitosan". Biomacromolecules. 6 (6): 2881–2894. doi: 10.1021/bm050410l. ISSN 1525-7797. PMID 16283704.
| History | | ||||
|---|---|---|---|---|---|
| Branches | |||||
| Biological concepts | |||||
| General concepts | |||||
| Basic techniques and tools |
| ||||
| Applications | |||||
| Interdisciplinary fields | |||||
| Lists | |||||
| Fields |
| ||
|---|---|---|---|
|
| This article about biological engineering is a stub. You can help Wikipedia by expanding it. |