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Clinical data | |
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Other names | Azidomorphine |
ATC code |
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Identifiers | |
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CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
CompTox Dashboard ( EPA) | |
ECHA InfoCard | 100.041.211 |
Chemical and physical data | |
Formula | C17H20N4O2 |
Molar mass | 312.373 g·mol−1 |
3D model ( JSmol) | |
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Azidomorphine [1] is an opiate analogue that is a derivative of morphine, where the 7,8 double bond has been saturated and the 6-hydroxy group has been replaced by an azide group. [2]
Azidomorphine binds with high affinity to the mu opioid receptor, [3] and is around 40× more potent than morphine in vivo. It has similar effects to morphine, including analgesia, sedation, and respiratory depression. However, its addiction liability has been found to be slightly lower than that of morphine in animal studies. [4] [5]
![]() | |
![]() | |
Clinical data | |
---|---|
Other names | Azidomorphine |
ATC code |
|
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
CompTox Dashboard ( EPA) | |
ECHA InfoCard | 100.041.211 |
Chemical and physical data | |
Formula | C17H20N4O2 |
Molar mass | 312.373 g·mol−1 |
3D model ( JSmol) | |
| |
| |
![]() ![]() |
Azidomorphine [1] is an opiate analogue that is a derivative of morphine, where the 7,8 double bond has been saturated and the 6-hydroxy group has been replaced by an azide group. [2]
Azidomorphine binds with high affinity to the mu opioid receptor, [3] and is around 40× more potent than morphine in vivo. It has similar effects to morphine, including analgesia, sedation, and respiratory depression. However, its addiction liability has been found to be slightly lower than that of morphine in animal studies. [4] [5]