The Asboe-Hansen sign (also known as "indirect Nikolsky sign'" [1] or "Nikolsky II sign" [1]) refers to the extension of a large blister to adjacent unblistered skin when pressure is put on the top of it. [2] [3] It is seen along with Nikolsky's sign, both used to assess the severity of some blistering diseases such as pemphigus vulgaris and severe bullous drug reactions. [4]
This sign is named for the Danish physician Gustav Asboe-Hansen (1917–1989), who first described it in 1960. [5]
It is considered an indirect diagnostic tool in toxic epidermal necrolysis (TEN).[ definition needed]
The Asboe-Hansen sign (also known as "indirect Nikolsky sign'" [1] or "Nikolsky II sign" [1]) refers to the extension of a large blister to adjacent unblistered skin when pressure is put on the top of it. [2] [3] It is seen along with Nikolsky's sign, both used to assess the severity of some blistering diseases such as pemphigus vulgaris and severe bullous drug reactions. [4]
This sign is named for the Danish physician Gustav Asboe-Hansen (1917–1989), who first described it in 1960. [5]
It is considered an indirect diagnostic tool in toxic epidermal necrolysis (TEN).[ definition needed]