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Names | |
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Preferred IUPAC name
(6Z,9Z,12Z,15Z)-1,1,1-Trifluorohenicosa-6,9,12,15-teraen-2-one | |
Other names
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Identifiers | |
3D model (
JSmol)
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ChemSpider | |
PubChem
CID
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UNII | |
CompTox Dashboard (
EPA)
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Properties | |
C21H31F3O | |
Molar mass | 356.473 g·mol−1 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Arachidonyl trifluoromethyl ketone (ATK) is an analog of arachidonic acid. [1] that inhibits some isoforms of the enzyme phospholipase A2. [2] Specifically it inhibits the 85 kDa cystolic PLA2 (cPLA2). [2]
It has been studied as a neuroprotective agent after spinal cord injury, [2] [3] and in animal models of multiple sclerosis. [4]
![]() | |
Names | |
---|---|
Preferred IUPAC name
(6Z,9Z,12Z,15Z)-1,1,1-Trifluorohenicosa-6,9,12,15-teraen-2-one | |
Other names
| |
Identifiers | |
3D model (
JSmol)
|
|
ChemSpider | |
PubChem
CID
|
|
UNII | |
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C21H31F3O | |
Molar mass | 356.473 g·mol−1 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Arachidonyl trifluoromethyl ketone (ATK) is an analog of arachidonic acid. [1] that inhibits some isoforms of the enzyme phospholipase A2. [2] Specifically it inhibits the 85 kDa cystolic PLA2 (cPLA2). [2]
It has been studied as a neuroprotective agent after spinal cord injury, [2] [3] and in animal models of multiple sclerosis. [4]