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Clinical data | |
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Other names | NGA0187; NGD-187; 16β-Acetoxy-3β,7β,11β-trihydroxy-5α-ergost-22E-en-6-one |
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ChemSpider | |
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CompTox Dashboard ( EPA) | |
Chemical and physical data | |
Formula | C30H48O6 |
Molar mass | 504.708 g·mol−1 |
3D model ( JSmol) | |
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Anicequol (developmental code names NGA0187, NGD-187) [1] is a naturally occurring ergostane steroid produced by Acremonium sp. TF-0356 which has nerve growth factor-like neurotrophic activity. [2] [3] [4] It was under investigation by Taisho Pharmaceutical in Japan for the treatment of cognitive disorders in the 1990s, but development was discontinued and the drug was never marketed. [5]
Anicequol (3) was independently isolated from Acremonium sp. TF-0356 and was assigned the trivial name NGA0187.
![]() | |
Clinical data | |
---|---|
Other names | NGA0187; NGD-187; 16β-Acetoxy-3β,7β,11β-trihydroxy-5α-ergost-22E-en-6-one |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
ChEMBL | |
CompTox Dashboard ( EPA) | |
Chemical and physical data | |
Formula | C30H48O6 |
Molar mass | 504.708 g·mol−1 |
3D model ( JSmol) | |
| |
|
Anicequol (developmental code names NGA0187, NGD-187) [1] is a naturally occurring ergostane steroid produced by Acremonium sp. TF-0356 which has nerve growth factor-like neurotrophic activity. [2] [3] [4] It was under investigation by Taisho Pharmaceutical in Japan for the treatment of cognitive disorders in the 1990s, but development was discontinued and the drug was never marketed. [5]
Anicequol (3) was independently isolated from Acremonium sp. TF-0356 and was assigned the trivial name NGA0187.