This article relies largely or entirely on a
single source. (June 2021) |
Anaerobic glycolysis is the transformation of glucose to lactate when limited amounts of oxygen (O2) are available. [1] Anaerobic glycolysis is an effective means of energy production only during short, intense exercise, [1] providing energy for a period ranging from 10 seconds to 2 minutes. This is much faster than aerobic metabolism. [2] The anaerobic glycolysis (lactic acid) system is dominant from about 10–30 seconds during a maximal effort. It replenishes very quickly over this period and produces 2 ATP molecules per glucose molecule, [3] or about 5% of glucose's energy potential (38 ATP molecules). [4] [5] The speed at which ATP is produced is about 100 times that of oxidative phosphorylation. [1]
Anaerobic glycolysis is thought to have been the primary means of energy production in earlier organisms before oxygen was at high concentration in the atmosphere and thus would represent a more ancient form of energy production in cells.
In mammals, lactate can be transformed by the liver back into glucose using the Cori cycle.
Fates of pyruvate under anaerobic conditions:
This article relies largely or entirely on a
single source. (June 2021) |
Anaerobic glycolysis is the transformation of glucose to lactate when limited amounts of oxygen (O2) are available. [1] Anaerobic glycolysis is an effective means of energy production only during short, intense exercise, [1] providing energy for a period ranging from 10 seconds to 2 minutes. This is much faster than aerobic metabolism. [2] The anaerobic glycolysis (lactic acid) system is dominant from about 10–30 seconds during a maximal effort. It replenishes very quickly over this period and produces 2 ATP molecules per glucose molecule, [3] or about 5% of glucose's energy potential (38 ATP molecules). [4] [5] The speed at which ATP is produced is about 100 times that of oxidative phosphorylation. [1]
Anaerobic glycolysis is thought to have been the primary means of energy production in earlier organisms before oxygen was at high concentration in the atmosphere and thus would represent a more ancient form of energy production in cells.
In mammals, lactate can be transformed by the liver back into glucose using the Cori cycle.
Fates of pyruvate under anaerobic conditions: