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Routes of administration | Oral |
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Chemical and physical data | |
Formula | C17H27NO |
Molar mass | 261.409 g·mol−1 |
3D model ( JSmol) | |
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Amixetrine ( INN) (brand name Somagest; developmental code name CERM-898) is a drug that was formerly marketed in France but is now no longer sold. [1] [2] According to various sources it has been said to be an anti-inflammatory, antidepressant, antispasmodic, anticholinergic, antihistamine, and antiserotonergic, but its definitive indications and pharmacology are unclear. [1] [2] The drug was first synthesized in 1969 and was introduced in France in 1972. [1] [2]
The treatment of isoamyl alcohol (1) with styrene (2) at -10°C with dropwise addition of tert-Butyl Hypobromite [1611-82-1] gives (2-bromo-1-(isopentyloxy)ethyl)benzene [5452-50-6] (3). Displacement of the halogen leaving group by pyrrolidine completes the synthesis of amixetrine (4).
![]() | |
Clinical data | |
---|---|
Routes of administration | Oral |
ATC code |
|
Legal status | |
Legal status |
|
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
ChEMBL | |
CompTox Dashboard ( EPA) | |
Chemical and physical data | |
Formula | C17H27NO |
Molar mass | 261.409 g·mol−1 |
3D model ( JSmol) | |
| |
| |
![]() ![]() |
Amixetrine ( INN) (brand name Somagest; developmental code name CERM-898) is a drug that was formerly marketed in France but is now no longer sold. [1] [2] According to various sources it has been said to be an anti-inflammatory, antidepressant, antispasmodic, anticholinergic, antihistamine, and antiserotonergic, but its definitive indications and pharmacology are unclear. [1] [2] The drug was first synthesized in 1969 and was introduced in France in 1972. [1] [2]
The treatment of isoamyl alcohol (1) with styrene (2) at -10°C with dropwise addition of tert-Butyl Hypobromite [1611-82-1] gives (2-bromo-1-(isopentyloxy)ethyl)benzene [5452-50-6] (3). Displacement of the halogen leaving group by pyrrolidine completes the synthesis of amixetrine (4).