Names | |
---|---|
Preferred IUPAC name
(6aS,7aS,8aR,8bR)-4-Methoxy-2,3,6a,7a,8a,8b-hexahydrocyclopenta[c]oxireno[2′′,3′′:4′,5′]furo[3′,2′:4,5]furo[2,3-h][1]benzopyran-1,10-dione | |
Identifiers | |
3D model (
JSmol)
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ChEBI | |
ChemSpider | |
PubChem
CID
|
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CompTox Dashboard (
EPA)
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| |
Properties | |
C17H12O7 | |
Molar mass | 328.276 g·mol−1 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Aflatoxin B1 exo-8,9-epoxide is a toxic metabolite of aflatoxin B1. It's formed by the action of cytochrome P450 enzymes in the liver. [1]
In the liver, aflatoxin B1 is metabolized to aflatoxin B1 exo-8,9-epoxide by the cytochrome P450 enzymes. The resulting epoxide can react with guanine in the DNA to cause DNA damage. [2]
Names | |
---|---|
Preferred IUPAC name
(6aS,7aS,8aR,8bR)-4-Methoxy-2,3,6a,7a,8a,8b-hexahydrocyclopenta[c]oxireno[2′′,3′′:4′,5′]furo[3′,2′:4,5]furo[2,3-h][1]benzopyran-1,10-dione | |
Identifiers | |
3D model (
JSmol)
|
|
ChEBI | |
ChemSpider | |
PubChem
CID
|
|
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C17H12O7 | |
Molar mass | 328.276 g·mol−1 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Aflatoxin B1 exo-8,9-epoxide is a toxic metabolite of aflatoxin B1. It's formed by the action of cytochrome P450 enzymes in the liver. [1]
In the liver, aflatoxin B1 is metabolized to aflatoxin B1 exo-8,9-epoxide by the cytochrome P450 enzymes. The resulting epoxide can react with guanine in the DNA to cause DNA damage. [2]