From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Beta-parvin is a
protein that in humans is encoded by the PARVB
gene .
[5]
[6]
[7]
Members of the parvin family, including PARVB,
PARVA and
PARVG , are actin-binding proteins associated with focal contacts.[supplied by OMIM]
[7]
References
^
a
b
c
GRCh38: Ensembl release 89: ENSG00000188677 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000022438 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000).
"Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics" . Genome Res . 10 (5): 703–13.
doi :
10.1101/gr.10.5.703 .
PMC
310876 .
PMID
10810093 .
^ Olski TM, Noegel AA, Korenbaum E (Feb 2001). "Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily". J Cell Sci . 114 (Pt 3): 525–38.
doi :
10.1242/jcs.114.3.525 .
PMID
11171322 .
^
a
b
"Entrez Gene: PARVB parvin, beta" .
Further reading
Dunham I, Shimizu N, Roe BA, et al. (1999).
"The DNA sequence of human chromosome 22" . Nature . 402 (6761): 489–95.
Bibcode :
1999Natur.402..489D .
doi :
10.1038/990031 .
PMID
10591208 .
Yamaji S, Suzuki A, Sugiyama Y, et al. (2001).
"A novel integrin-linked kinase-binding protein, affixin, is involved in the early stage of cell-substrate interaction" . J. Cell Biol . 153 (6): 1251–64.
doi :
10.1083/jcb.153.6.1251 .
PMC
2192033 .
PMID
11402068 .
Korenbaum E, Olski TM, Noegel AA (2002). "Genomic organization and expression profile of the parvin family of focal adhesion proteins in mice and humans". Gene . 279 (1): 69–79.
doi :
10.1016/S0378-1119(01)00743-0 .
PMID
11722847 .
Yamaji S, Suzuki A, Kanamori H, et al. (2002). "Possible role of ILK-affixin complex in integrin-cytoskeleton linkage during platelet aggregation". Biochem. Biophys. Res. Commun . 297 (5): 1324–31.
doi :
10.1016/S0006-291X(02)02381-1 .
PMID
12372433 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
Rosenberger G, Jantke I, Gal A, Kutsche K (2003).
"Interaction of alphaPIX (ARHGEF6) with beta-parvin (PARVB) suggests an involvement of alphaPIX in integrin-mediated signaling" . Hum. Mol. Genet . 12 (2): 155–67.
doi :
10.1093/hmg/ddg019 .
PMID
12499396 .
Collins JE, Goward ME, Cole CG, et al. (2003).
"Reevaluating human gene annotation: a second-generation analysis of chromosome 22" . Genome Res . 13 (1): 27–36.
doi :
10.1101/gr.695703 .
PMC
430954 .
PMID
12529303 .
Mishima W, Suzuki A, Yamaji S, et al. (2004).
"The first CH domain of affixin activates Cdc42 and Rac1 through alphaPIX, a Cdc42/Rac1-specific guanine nucleotide exchanging factor" . Genes Cells . 9 (3): 193–204.
doi :
10.1111/j.1356-9597.2004.00717.x .
PMID
15005707 .
Yamaji S, Suzuki A, Kanamori H, et al. (2004).
"Affixin interacts with alpha-actinin and mediates integrin signaling for reorganization of F-actin induced by initial cell-substrate interaction" . J. Cell Biol . 165 (4): 539–51.
doi :
10.1083/jcb.200308141 .
PMC
2172344 .
PMID
15159419 .
Zhang Y, Chen K, Tu Y, Wu C (2004).
"Distinct roles of two structurally closely related focal adhesion proteins, alpha-parvins and beta-parvins, in regulation of cell morphology and survival" . J. Biol. Chem . 279 (40): 41695–705.
doi :
10.1074/jbc.M401563200 .
PMID
15284246 .
Mongroo PS, Johnstone CN, Naruszewicz I, et al. (2004).
"Beta-parvin inhibits integrin-linked kinase signaling and is downregulated in breast cancer" . Oncogene . 23 (55): 8959–70.
doi :
10.1038/sj.onc.1208112 .
PMID
15467740 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7.
doi :
10.1101/gr.2596504 .
PMC
528928 .
PMID
15489334 .
Matsuda C, Kameyama K, Tagawa K, et al. (2005).
"Dysferlin interacts with affixin (beta-parvin) at the sarcolemma" . J. Neuropathol. Exp. Neurol . 64 (4): 334–40.
doi :
10.1093/jnen/64.4.334 .
PMID
15835269 .
Ewing RM, Chu P, Elisma F, et al. (2007).
"Large-scale mapping of human protein-protein interactions by mass spectrometry" . Mol. Syst. Biol . 3 (1): 89.
doi :
10.1038/msb4100134 .
PMC
1847948 .
PMID
17353931 .