2nd Avenue or Second Avenue may refer to:

Places (including transport stations)

• 2nd Avenue & Abilene station, a light rail station in Aurora, Colorado, U.S.
• 2nd Avenue Lofts, a historic building in the Central Business District, Saskatoon, Saskatchewan, Canada
• Second Avenue Deli, kosher delicatessen in Manhattan, NY, U.S.
• Irving and 2nd Avenue station, a light rail stop in San Francisco, U.S.
• Second Avenue (IND Sixth Avenue Line), a station on the New York City Subway

Roads and transportation

• 2nd Avenue, an arterial road in Whitehorse, Yukon, Canada
• M15 (New York City bus), a bus route in Manhattan that runs on First and Second Avenue
• Second Avenue, a neighborhood of Albany, New York, U.S.
• Second Avenue (IND Sixth Avenue Line), a New York City Subway station
• Second Avenue (Brooklyn), a street in Brooklyn, U.S.
• Second Avenue (Manhattan), a street in New York, U.S.
• Second Avenue ( Nashville, Tennessee), site of a Christmas Day 2020 explosion
• Second Avenue (Pittsburgh), a street in Pittsburgh, PA, U.S.
• Second Avenue Subway, or IND Second Avenue Line, a line in the New York City Subway

Defunct roads and transportation

• IRT Second Avenue Line, or Second Avenue El, a former elevated railway
• Second Avenue Railroad, a former street railway company

Arts, entertainment, and media

• 2nd Avenue (album), by No Justice, 2010
• Second Avenue (album), by Lisa Moscatiello, 2000
• "Second Avenue" (song), a 1974 song written by Tim Moore and recorded by Art Garfunkel
• 2nd Avenue (TV channel), a defunct television network in the Philippines
• On Second Avenue, a Yiddish American musical theatre production

See also

• All pages with titles containing Second Avenue
• All pages with titles containing 2nd Avenue
• 2nd Street (disambiguation)

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