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Names | |||
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Preferred IUPAC name
2-Bromopyridine | |||
Identifiers | |||
3D model (
JSmol)
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ChEBI | |||
ChEMBL | |||
ChemSpider | |||
ECHA InfoCard | 100.003.311 | ||
EC Number |
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PubChem
CID
|
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UNII | |||
CompTox Dashboard (
EPA)
|
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Properties | |||
C5H4NBr | |||
Molar mass | 158.00 | ||
Appearance | colorless liquid | ||
Boiling point | 194.8 °C | ||
Related compounds | |||
Related compounds
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2-Chloropyridine 3-Bromopyridine | ||
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
2-Bromopyridine is an aryl bromide and isomer of bromopyridine with the formula BrC5H4N. It is a colorless liquid that is used as an intermediate in organic synthesis. It can be prepared from 2-aminopyridine via diazotization followed by bromination. [1]
2-Bromopyridine reacts with butyllithium to give 2-lithiopyridine, [2] which is a versatile reagent. [3] Pyrithione can be prepared in a two-step synthesis from 2-bromopyridine by oxidation to the N-oxide with a suitable peracid followed by substitution using either sodium dithionite or sodium sulfide with sodium hydroxide to introduce the thiol functional group. [4]
Organometallic addition to benzophenone followed by catalytic hydrogenation is the synthesis of pipradrol.
| |||
Names | |||
---|---|---|---|
Preferred IUPAC name
2-Bromopyridine | |||
Identifiers | |||
3D model (
JSmol)
|
|||
ChEBI | |||
ChEMBL | |||
ChemSpider | |||
ECHA InfoCard | 100.003.311 | ||
EC Number |
| ||
PubChem
CID
|
|||
UNII | |||
CompTox Dashboard (
EPA)
|
|||
| |||
| |||
Properties | |||
C5H4NBr | |||
Molar mass | 158.00 | ||
Appearance | colorless liquid | ||
Boiling point | 194.8 °C | ||
Related compounds | |||
Related compounds
|
2-Chloropyridine 3-Bromopyridine | ||
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
2-Bromopyridine is an aryl bromide and isomer of bromopyridine with the formula BrC5H4N. It is a colorless liquid that is used as an intermediate in organic synthesis. It can be prepared from 2-aminopyridine via diazotization followed by bromination. [1]
2-Bromopyridine reacts with butyllithium to give 2-lithiopyridine, [2] which is a versatile reagent. [3] Pyrithione can be prepared in a two-step synthesis from 2-bromopyridine by oxidation to the N-oxide with a suitable peracid followed by substitution using either sodium dithionite or sodium sulfide with sodium hydroxide to introduce the thiol functional group. [4]
Organometallic addition to benzophenone followed by catalytic hydrogenation is the synthesis of pipradrol.