Names | |
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IUPAC name
1,3-oxazol-2-amine
| |
Other names
| |
Identifiers | |
3D model (
JSmol)
|
|
ChemSpider | |
ECHA InfoCard | 100.128.287 |
EC Number |
|
MeSH | 2-aminooxazole |
PubChem
CID
|
|
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C3H4N2O | |
Molar mass | 84.08 g/mol |
Appearance | White solid (at 97% purity) |
Density | 1.2±0.1 g/cm3 |
Melting point | 90-95 °C |
Boiling point | 186.7±23.0 °C |
Vapor pressure | 0.7±0.4 mmHg |
Hazards | |
GHS labelling: | |
Warning | |
H315, H319, H335 | |
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, P501 | |
Flash point | 66.7±22.6 °C |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
2-Aminooxazole is a heterocyclic organic compound, belonging to the class of oxazoles. It is a five-membered ring structure containing one oxygen and two nitrogen atoms.
2-Aminooxazole contains a primary amine group which can participate in various reactions like protonation, acylation, or alkylation. The oxazole ring can also show reactions like ring expansion, electrophilic substitution, etc. [2] and also contributes aromatic character and stability to the molecule.
2-Aminooxazole possesses antimicrobial properties against various fungal and bacterial strains especially against Tuberculosis-causing Mycobacterium tuberculosis. [3]
The amine group of 2-Aminooxazole can potentially link with different molecules, making it a potential candidate for drug synthesis in antitubercular medicinal chemistry. [4]
2-Aminooxazole has also been hypothesised to have played a role in chemical evolution as a precursor of RNA nucleotides. [5]
Names | |
---|---|
IUPAC name
1,3-oxazol-2-amine
| |
Other names
| |
Identifiers | |
3D model (
JSmol)
|
|
ChemSpider | |
ECHA InfoCard | 100.128.287 |
EC Number |
|
MeSH | 2-aminooxazole |
PubChem
CID
|
|
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C3H4N2O | |
Molar mass | 84.08 g/mol |
Appearance | White solid (at 97% purity) |
Density | 1.2±0.1 g/cm3 |
Melting point | 90-95 °C |
Boiling point | 186.7±23.0 °C |
Vapor pressure | 0.7±0.4 mmHg |
Hazards | |
GHS labelling: | |
Warning | |
H315, H319, H335 | |
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, P501 | |
Flash point | 66.7±22.6 °C |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
2-Aminooxazole is a heterocyclic organic compound, belonging to the class of oxazoles. It is a five-membered ring structure containing one oxygen and two nitrogen atoms.
2-Aminooxazole contains a primary amine group which can participate in various reactions like protonation, acylation, or alkylation. The oxazole ring can also show reactions like ring expansion, electrophilic substitution, etc. [2] and also contributes aromatic character and stability to the molecule.
2-Aminooxazole possesses antimicrobial properties against various fungal and bacterial strains especially against Tuberculosis-causing Mycobacterium tuberculosis. [3]
The amine group of 2-Aminooxazole can potentially link with different molecules, making it a potential candidate for drug synthesis in antitubercular medicinal chemistry. [4]
2-Aminooxazole has also been hypothesised to have played a role in chemical evolution as a precursor of RNA nucleotides. [5]