Names | |
---|---|
Preferred IUPAC name
2,4-Dihydroxybenzoic acid | |
Other names
β-Resorcylic acid
β-Resorcinolic acid p-Hydroxysalicylic acid 2,4-DHBA | |
Identifiers | |
3D model (
JSmol)
|
|
ChEMBL | |
ChemSpider | |
DrugBank | |
ECHA InfoCard | 100.001.770 |
PubChem
CID
|
|
UNII | |
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C7H6O4 | |
Molar mass | 154.12 g/mol |
Melting point | 229 °C (444 °F; 502 K) [2] |
Acidity (pKa) | 3.11, 8.55, 14.0 [1] |
Hazards | |
GHS labelling: [3] | |
Warning | |
H315, H319, H335 | |
P261, P280, P302+P352, P305+P351+P338 | |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
2,4-Dihydroxybenzoic acid (Resochin, [4] sontochin, [4] SN-7619, [4] β-resorcylic acid) is a dihydroxybenzoic acid.
As a resorcylic acid, it is one of the three isomeric crystalline acids that are both carboxyl derivatives of resorcinol and dihydroxy derivatives of benzoic acid. [5] Synthesis from resorcinol is via the Kolbe-Schmitt reaction. [6]
It is a degradation product of cyanidin glycosides from tart cherries in cell cultures. [7] It is also a metabolite found in human plasma after cranberry juice consumption. [8]
Resochin is especially effective against avian malaria. Because the initial testing during the chemical development process used avian malaria its efficacy was recognised immediately. [4]
Names | |
---|---|
Preferred IUPAC name
2,4-Dihydroxybenzoic acid | |
Other names
β-Resorcylic acid
β-Resorcinolic acid p-Hydroxysalicylic acid 2,4-DHBA | |
Identifiers | |
3D model (
JSmol)
|
|
ChEMBL | |
ChemSpider | |
DrugBank | |
ECHA InfoCard | 100.001.770 |
PubChem
CID
|
|
UNII | |
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C7H6O4 | |
Molar mass | 154.12 g/mol |
Melting point | 229 °C (444 °F; 502 K) [2] |
Acidity (pKa) | 3.11, 8.55, 14.0 [1] |
Hazards | |
GHS labelling: [3] | |
Warning | |
H315, H319, H335 | |
P261, P280, P302+P352, P305+P351+P338 | |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
2,4-Dihydroxybenzoic acid (Resochin, [4] sontochin, [4] SN-7619, [4] β-resorcylic acid) is a dihydroxybenzoic acid.
As a resorcylic acid, it is one of the three isomeric crystalline acids that are both carboxyl derivatives of resorcinol and dihydroxy derivatives of benzoic acid. [5] Synthesis from resorcinol is via the Kolbe-Schmitt reaction. [6]
It is a degradation product of cyanidin glycosides from tart cherries in cell cultures. [7] It is also a metabolite found in human plasma after cranberry juice consumption. [8]
Resochin is especially effective against avian malaria. Because the initial testing during the chemical development process used avian malaria its efficacy was recognised immediately. [4]