From Wikipedia, the free encyclopedia
(Redirected from 2,3-diaminopropionate)
l-2,3-Diaminopropanoic acid
Names
IUPAC name
3-Amino-L-alanine
Systematic IUPAC name
(2S)-2,3-Diaminopropanoic acid
Identifiers
3D model ( JSmol)
ChEBI
ChemSpider
KEGG
PubChem CID
UNII
  • InChI=1S/C3H8N2O2/c4-1-2(5)3(6)7/h2H,1,4-5H2,(H,6,7)/t2-/m0/s1
    Key: PECYZEOJVXMISF-REOHCLBHSA-N
  • C([C@@H](C(=O)O)N)N
Properties
C3H8N2O2
Molar mass 104.109 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

2,3-Diaminopropionic acid (2,3-diaminopropionate, Dpr) [1] is a non-proteinogenic amino acid found in certain secondary metabolites, including zwittermicin A [2] and tuberactinomycin. [3]

Biosynthesis

2,3-Diaminopropionate is formed by the pyridoxal phosphate (PLP) mediated amination of serine.

Biosynthesis of l-2,3 Diaminopropionate

References

  1. ^ Frenkel-Pinter M, Haynes JW, C M, Petrov AS, Burcar BT, Krishnamurthy R, et al. (August 2019). "Selective incorporation of proteinaceous over nonproteinaceous cationic amino acids in model prebiotic oligomerization reactions". Proceedings of the National Academy of Sciences of the United States of America. 116 (33): 16338–16346. doi: 10.1073/pnas.1904849116. PMC  6697887. PMID  31358633.
  2. ^ Rogers EW, Molinski TF (February 2007). "Asymmetric synthesis of diastereomeric diaminoheptanetetraols. A proposal for the configuration of (+)-zwittermicin a". Organic Letters. 9 (3): 437–40. doi: 10.1021/ol062804a. PMC  2729442. PMID  17249781.
  3. ^ Thomas MG, Chan YA, Ozanick SG (September 2003). "Deciphering tuberactinomycin biosynthesis: isolation, sequencing, and annotation of the viomycin biosynthetic gene cluster". Antimicrobial Agents and Chemotherapy. 47 (9): 2823–30. doi: 10.1128/AAC.47.9.2823-2830.2003. PMC  182626. PMID  12936980.
From Wikipedia, the free encyclopedia
(Redirected from 2,3-diaminopropionate)
l-2,3-Diaminopropanoic acid
Names
IUPAC name
3-Amino-L-alanine
Systematic IUPAC name
(2S)-2,3-Diaminopropanoic acid
Identifiers
3D model ( JSmol)
ChEBI
ChemSpider
KEGG
PubChem CID
UNII
  • InChI=1S/C3H8N2O2/c4-1-2(5)3(6)7/h2H,1,4-5H2,(H,6,7)/t2-/m0/s1
    Key: PECYZEOJVXMISF-REOHCLBHSA-N
  • C([C@@H](C(=O)O)N)N
Properties
C3H8N2O2
Molar mass 104.109 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

2,3-Diaminopropionic acid (2,3-diaminopropionate, Dpr) [1] is a non-proteinogenic amino acid found in certain secondary metabolites, including zwittermicin A [2] and tuberactinomycin. [3]

Biosynthesis

2,3-Diaminopropionate is formed by the pyridoxal phosphate (PLP) mediated amination of serine.

Biosynthesis of l-2,3 Diaminopropionate

References

  1. ^ Frenkel-Pinter M, Haynes JW, C M, Petrov AS, Burcar BT, Krishnamurthy R, et al. (August 2019). "Selective incorporation of proteinaceous over nonproteinaceous cationic amino acids in model prebiotic oligomerization reactions". Proceedings of the National Academy of Sciences of the United States of America. 116 (33): 16338–16346. doi: 10.1073/pnas.1904849116. PMC  6697887. PMID  31358633.
  2. ^ Rogers EW, Molinski TF (February 2007). "Asymmetric synthesis of diastereomeric diaminoheptanetetraols. A proposal for the configuration of (+)-zwittermicin a". Organic Letters. 9 (3): 437–40. doi: 10.1021/ol062804a. PMC  2729442. PMID  17249781.
  3. ^ Thomas MG, Chan YA, Ozanick SG (September 2003). "Deciphering tuberactinomycin biosynthesis: isolation, sequencing, and annotation of the viomycin biosynthetic gene cluster". Antimicrobial Agents and Chemotherapy. 47 (9): 2823–30. doi: 10.1128/AAC.47.9.2823-2830.2003. PMC  182626. PMID  12936980.

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