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Atopic dermatitis article. This is not a forum for general discussion of the article's subject. |
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Ideal sources for Wikipedia's health content are defined in the guideline
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Atopic Eczema DOES have a definite cause ( lectin) but also has many mitigating factors which are often misidentified as "causes". Millions of people don't take the precautions bellow yet don't have Eczema - suggesting that eczema is not caused by not following them:
Atopic Eczema also has a definite cure. It is one that involves a temporary lifestyle (dietary) change. Just because the cure isn't a cream, a drink or a few pills doesn't mean that it cannot be THE CURE. Logic would define that the cure to a non congenital disease would involve a reversal, removal or some sort of antagonistic action against the Cause.
Laoseb97 (
talk) 15:02, 12 May 2013 (UTC)
@ Triougd: "Adding your sources shouldn't be too hard." IMHO it is. This is mainly because I didn't get the information from only one source- making it hard give a better citation. The majoriy of the things that I have edited in, have come from the sources that I have already given and the hyperlinks to other wikipedia pages. My edits to this article are basically the results of weeding through the web and are the bigger picture from all the sources.
Here are some half-misleading (Flawed) external sources I came across along the way that contribute as deductive evidence (with notable qoutes).
http://www.paleoplan.com/2011/03-30/why-no-grains-and-legumes/
http://simplehomemade.net/how-a-simple-diet-change-cured-infant-eczema/
@ Everyone: Please help add better citations for this article Laoseb97 ( talk) 17:46, 14 May 2013 (UTC)
@ Triougd: Thanks for replying and for your links you recommended to me.
I have a few clarifications and queries to make;
Laoseb97 ( talk) 19:17, 15 May 2013 (UTC)
Thank you for the links again - I have read them.
I understand the importance of sources in medical articles and I am sorry that my edits were substandard (in terms of what you said).
I think you said something about "alternative medicine" - I like the name (joke). Seriously though, In view of all that we have discussed , I am now contemplating making a new page called "Lectin hypothesis" as an alternative medicine stub-thing - I will take what i said on this article, on there and leave it as a hypothesis until somebody finds a black and white, peer reviewed, reliable source that supports it. Then I will collapse the page into "Atopic Dermatitis" . Meanwhile you could then revert (I don't know how to revert) the page, to your favorite archived version. Would you be in favor of that? Also any advice/ cautions would be appreciated.
I haven't been able to track down any credible source on it at all. I care about finding out exactly which hypothesis is the correct one, not whether or not that one is - Thanks for trying anyway.
Laoseb97 (
talk) 18:59, 16 May 2013 (UTC)
Oh, ok.
Ok.
In the light of your advice, I not going to make the new page (I know It is far more advanced than current sources suggest ( It counts as OR). I am better off not writing it on Wikipedia. Ill try and find some where else to post it- I might serve Better as Original research.
Thanks.
Laoseb97 (
talk) 18:38, 17 May 2013 (UTC)
I read this page out of interest after a patient decided they were an expert on Eczema after reading this Wikipedia article. I found a lot of factual errors in the article no doubt contributing to the widespread misconceptions about the causes of eczema.
Perhaps the editors for this page should have a thorough read of: http://dermnetnz.org/dermatitis/atopic-causes.html (and associated pages) which presents a more accurate view of the causes of eczema. It is written and edited by expert dermatologists. —Preceding unsigned comment added by 121.98.223.127 ( talk) 11:42, 20 January 2011 (UTC)
Completely agree with you. To read about dietary changes as treatment of AD means to be out of time. The main cause of AD is mutation of filaggrin which is present in about half cases, but the pathogenesis is complex. Vorticus ( talk) 22:04, 1 May 2016 (UTC)
Removing the nonsense about psyche and emotions barring a scholarly cite beyond Sontag, who was talking about popular culture reacting to disease, and not disease reacting to popular culture.
I don't know what you removed, but stress, including by extension emotionally induced stress, plays a major role in aggravating, and even causing (according to some) atopic dermatitis. Ken K. Smith (a.k.a. Thin Smek) ( talk) 16:33, 19 December 2018 (UTC)
also, it is NOT the same as a candida infection... if there is a relationship, then the previous author needs to provide a scholarly citation See: http://www.niams.nih.gov/hi/topics/dermatitis/
"neurodermatitis" should definitely be subsumed by "atopic dermatitis". AFAIK the latter (or equivalently, "atopic eczema") is now the preferred term.
References
1. regarding the merge with atopy: not a good idea, IMO, since atopic eczema is not the same thing as atopy, and the main eczema entry needs to be able to point to entries on each type.
2. regarding the merge with neurodermatitis: I argue against. There is some confusion on this issue, since in central Europe atopic eczema seems to be referred to -- some of the time -- as disseminated neurodermatitis. In the English speaking countries (and others?), however, neurodermatitis (or localized neurodermatitis) refers to lichen simplex chronicus and prurigo nodularis, eczemas either self-inflicted or of unknown etiology, but quite distinct from atopic dermatitis.
I think the entry on neurodermatitis should be returned to the original lichen simplex chronicus that has been overwritten with atopic stuff. V.B. 05:06, 9 October 2006 (UTC)V.B.
do not merge with atopy, they are distinct. -- Coroebus 19:21, 30 October 2006 (UTC)
Dont merge with atopy because as already mentioned atopy is a immune state rather than a disease in its self. Also the current trend in research is to actually group it with other inflammatory diseases such as crohns disease and leprosy, this is because of research into the role of barrier function in these diseases. Moreover as already mentioned atopy is defined as over production of IgE, well in 20-30% of cases of AD there is no IgE overproduction.
If you look up this entry on German Wiki, you will find that the neurodermitis term is the old one that is being superceded. However, it seems in common usage still. 170.215.67.24 05:26, 9 October 2006 (UTC)V.B.
I created a disambiguation page in reference to neurodermatitis, directing folks to either lichen/prurigo, or to atopic eczema. 170.215.67.24 22:53, 14 October 2006 (UTC)V.B.
"Although many people are intimidated by the term 'steroids,' their proper use can result in atopic dermatitis being brought under control."
This statement is not NPOV, and tends towards the irresponsible. Yes, strong steroids will superficially "cure" most skin problems. But there are also serious risks of systemic side-effects. It is important to use these drugs with care, and only use the minimum necessary, for a minimum time, to get the needed results.
"Alternative medicines may (illegally) contain very strong steroids"
Sure, they may. But most alternative medicines for eczema probably have no steroids. For example, GLA (
gamma-linolenic acid) a fatty acid found in evening primrose oil, black currant oil and
borage, is not a steriod. -
69.87.204.151 23:48, 2 March 2007 (UTC)
{{
cite journal}}
: CS1 maint: multiple names: authors list (
link)){{
cite journal}}
: Unknown parameter |month=
ignored (
help). Also same reasons for withdrawal in cyclical pre-menstrual breast discomfort in women.
[1])
{{
cite journal}}
: CS1 maint: multiple names: authors list (
link) concludes that "Dietary GLA-supplementation could not prevent AD"{{
cite journal}}
: CS1 maint: multiple names: authors list (
link) - concluded that " the overall response to borage oil did not reach statistical significance" and I note the study design description that: "Use of topical diflucortolone-21-valerate cream was allowed as rescue medication,".{{
cite journal}}
: Unknown parameter |month=
ignored (
help) - "Conclusion gamma linolenic acid is not beneficial in atopic dermatitis"The main short term side effects of using overly strong topical steroid are well-documented, because they can be extremely nasty. Using topical steroid over the long term (decades) causes permanently and drastically: thinned skin, reduced cortisone production, reduced sensitively to cortisone, increased inflammation, breakdown of skin due to collagen loss and replacement inhibition, and higher risk of cancer. However, the strength of steroid used is proportional to the severity of these long term side effects, using very weak steroid should have little effect, whereas very strong steroid may bring this effects forwards several years.
So a doctor will normally try to use the least strength for the shortest time, and promote alternative solutions such as avoiding irritants and moisturising x amount of times a day in order to reduce the need for (strong) steroids. There is a benefit versus risk logic used for deciding what strength to use, and when.
The fear of using too much steroid is quite rational to a degree, but perhaps aggravated by learning how certain sport competitions were won by steroid enhanced cheaters who then experienced extreme medical conditions. Also the strong psychological correlation between cheat and bad can be more like cheat equals abominable when it comes to one's favourite sports. Ken K. Smith (a.k.a. Thin Smek) ( talk) 17:09, 19 December 2018 (UTC)
Tagging User:Davidruben. Ken K. Smith (a.k.a. Thin Smek) ( talk) 17:19, 17 January 2019 (UTC)
NEJM review http://content.nejm.org/cgi/content/short/358/14/1483 JFW | T@lk 14:43, 6 April 2008 (UTC)
The umbrella term for inflammatory skin reactions is dermatitis, subdivisions are for example contact dermatitis and eczema. Eczema is further subdivided into atopic eczema and non-atopic eczema (depending on IgE levels)
Historically eczema, neurodermitis (neurodermatitis in Engl.) and atopic eczema were used as synonyms. Therefore the article on neurodermatitis should be deleted. A few lines in the atopic eczema article should suffice.
Johansson SG. Revised, global nomenclature for allergy. Unambiguous terms create clarity and prevent misunderstandings. Lakartidningen.2006;103:379-83. (in Swedish) Haddendaddendoedenda ( talk) 20:25, 15 February 2009 (UTC)
There is a journal article linked from the Wiki page on Dental amalgam controversy which concerns "The Beneficial Effect of Amalgam Replacement on Health in Patients with Autoimmunity". Article here. Atopic eczema is discussed as one of the disorders that can be affected (albeit, it is the one with the "lowest rate" of improvement). Asat ( talk) 20:57, 16 November 2009 (UTC)
Amalgam fillings have recently been banned in New Zealand, where I live, because it's now considered hazardous. Before that, it was considered perfectly healthy. Ken K. Smith (a.k.a. Thin Smek) ( talk) 16:03, 19 December 2018 (UTC)
Tagging User:Asat. Ken K. Smith (a.k.a. Thin Smek) ( talk) 17:20, 17 January 2019 (UTC)
We have this paper but it is not a review Rapaport, MJ (2003 May-Jun). "Corticosteroid addiction and withdrawal in the atopic: the red burning skin syndrome". Clinics in dermatology. 21 (3): 201–14.
PMID
12781438. {{
cite journal}}
: Check date values in: |date=
(
help); Unknown parameter |coauthors=
ignored (|author=
suggested) (
help)
Doc James (
talk ·
contribs ·
email) 05:17, 9 August 2011 (UTC)
What do you mean, "it's not a review?" — Preceding
unsigned comment added by
98.102.223.174 (
talk) 21:30, 8 January 2013 (UTC)
Bad reference: 16: "^ a b c . pp. 52–56. doi:10.2340/00015555-0565." ? The doi link goes to a DOI Not Found page.
Not-referenced: The first paragraph of Prevention -> Diet is not cited: "Originally controversial, the association of food allergy with atopic dermatitis has now been clearly demonstrated. Many common food allergens can trigger an allergic reaction: such as milk, nuts, cheese, tomatoes, wheat, yeast, soy, and corn. Many of these allergens are common ingredients in grocery store products (especially corn syrup, which is a sugar substitute). Specialty health food stores often carry products that do not contain common allergens."
I would like to see citations for each of those food items listed relative to atopic dermatitis. Thanks anyone working on this. — Preceding unsigned comment added by 75.97.112.151 ( talk) 14:10, 26 August 2011 (UTC)
"To combat the severe dryness associated with atopic dermatitis, a high-quality, dermatologist-approved moisturizer should be used daily." I'm not sure what the source for this sentence is. I used to use high-quality, dermatologist-approved moisturizer. After a while I decided it was pretty expensive and tried a form of petroleum jelly (similar ingredients) from sort-of the Dutch equivalent of the dollar store (actually just a store with cheap goods, not everything the same price). Anyway, this stuff is about 10 times as cheap and comparable to the "high-quality, dermatologist-approved moisturizer", at least for me. So I'd like to know the source for this sentence. W3ird N3rd ( talk) 04:11, 2 May 2012 (UTC)
Dairy/milk does contain more than just lectins. I think it is a mistake to reduce dairy/milk to lectins, there are other substances in milk (e.g. proteins like lactose, casein, albumin, immunogloblin) that can cause problems. There should be IMHO a dairy section. Tony Mach ( talk) 05:08, 13 May 2013 (UTC)
Currently the lack of vitamins is not described as a possible reason for atopic dermatitis, although there is indication that it plays a role:
References
I looked into this page because I had a sudden attack of this condition several days ago. My arm looked exactly like this picture. The rash appeared in half a minute (!) However, I am 35 and never had food allergies. This attack was seemingly caused by an antibiotic which was prescribed to me (I never took it before). My mother gave me hydrocortysone which worked immediately. But my arm was badly scarred after it, and by now there are still slight traces of scars. The article speaks of the condition as of chronic, but my case was apparently acute. And it says nothing of reaction to antibiotics. 93.80.113.253 ( talk) 14:52, 7 February 2015 (UTC)
"Things that commonly make it worse include wool clothing, soaps" - does this refer to Soap or Detergent? Most things labelled 'soap' in a supermarket are not traditional soap but contain detergents such as Sodium laureth sulfate, which is indeed a known irritant (as mentioned on its page). -- Melarish ( talk) 17:37, 8 November 2015 (UTC)
doi:10.1016/S0140-6736(15)00149-X JFW | T@lk 13:12, 11 March 2016 (UTC)
The following content are from evidence based management practice, unfortunately everything isn't referenced. Those who understand wikipedia rules do help to salvage the following. Thank you.
The advantage of the emollients is that it creates an artificial skin barrier to the impaired stratum corneum and retains hydration of the epidermis; when the water component evaporates, it cools the skin, this tends to decrease the blood supply to the skin and to lessen the release of inflammatory mediators, thus relieves the itch. The main function of emollients is possible prevention of aggravating factors of eczema.
especially microbes that have been associated with the following: Th1 type immunity, generation of TGF-, which suppresses Th2 responses, and induction of oral tolerance and IgA production, an essential component of mucosal immune defence.
In a study of mothers who have had at least one first-degree relative (or partner) with atopic disease (eczema, rhinitis, or asthma), the mother was given lactobacillus GG prenatally and their infants were given it postnatally for 6 months. At the age of 2 years in those receiving lactobacillus GG, the incidence of atopic eczema was 23% vs. 46% in controls, a highly significant result. It has recently been shown that this benefit is maintained at 4 years followup. [1] [2]
Corticosteroids have a strong anti-inflammatory action and this is the reason why they are so effective in eczema. The cellular effects are due to the binding of the glucocorticosteroids (GCS) to the cytosolic GCS receptor in nucleated cells. Since most cells have these receptors, the effects of the GCS are multiple. Once the steroids have bound to the receptor, there is conformational change in the GCS receptor complex; which moves to the nucleus. The GCS complex now binds to segments of DNA cell glucocorticoid-responsive elements. As a result, certain parts of the genome are affected, leading to increased or decreased transcription, with resulting increased or decreased cytokine production. GCS will also bind to NF-kB, which has been shown to be a regulator for many cytokines and cell adhesion molecules. Binding of GCS to NF-kB will switch off cytokine production, particularly of those cytokines concerned with T-cell-mediated inflammation. [3] [4] The loss of existing collagen and inhibition of new collagen formation and making the skin thinner is the main side-effect of topical steroids.
ciclosporin (risk factors includes nephrotoxic & carcinogenic), methotrexate, interferon gamma-1b, mycophenolate mofetil (risk factors include bone marrow suppression and the risks of malignancy)
Topical or systemic triazole antifungal preparations are also used appropriate for combating Pityrosporum orbiculare.
References
AFP
was invoked but never defined (see the
help page).MSR
was invoked but never defined (see the
help page).I noticed much better pictures on google images search for this Topic (actually, for Atopic Eczema itself). Photos showing dime- to quarter-sized red disks with several small whitish or yellowish bumps in the middle. Someone I know has a small outbreak, hence my interest. How does a main, single photo usually get swapped out on wikipedia? Ok to link to or display in an article 2 or more photos in wikimedia? Thank you all for your time. Vid2vid ( talk) 07:37, 24 November 2018 (UTC)
Will atopic dermatitis stay on your forever? 2405:ACC0:1102:B33A:3D00:B98E:7B49:554B ( talk) 10:33, 3 March 2023 (UTC)
This is the
talk page for discussing improvements to the
Atopic dermatitis article. This is not a forum for general discussion of the article's subject. |
Article policies
|
Find medical sources: Source guidelines · PubMed · Cochrane · DOAJ · Gale · OpenMD · ScienceDirect · Springer · Trip · Wiley · TWL |
This
level-5 vital article is rated B-class on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: |
|||||||||||||||||
|
Ideal sources for Wikipedia's health content are defined in the guideline
Wikipedia:Identifying reliable sources (medicine) and are typically
review articles. Here are links to possibly useful sources of information about Atopic dermatitis.
|
Atopic Eczema DOES have a definite cause ( lectin) but also has many mitigating factors which are often misidentified as "causes". Millions of people don't take the precautions bellow yet don't have Eczema - suggesting that eczema is not caused by not following them:
Atopic Eczema also has a definite cure. It is one that involves a temporary lifestyle (dietary) change. Just because the cure isn't a cream, a drink or a few pills doesn't mean that it cannot be THE CURE. Logic would define that the cure to a non congenital disease would involve a reversal, removal or some sort of antagonistic action against the Cause.
Laoseb97 (
talk) 15:02, 12 May 2013 (UTC)
@ Triougd: "Adding your sources shouldn't be too hard." IMHO it is. This is mainly because I didn't get the information from only one source- making it hard give a better citation. The majoriy of the things that I have edited in, have come from the sources that I have already given and the hyperlinks to other wikipedia pages. My edits to this article are basically the results of weeding through the web and are the bigger picture from all the sources.
Here are some half-misleading (Flawed) external sources I came across along the way that contribute as deductive evidence (with notable qoutes).
http://www.paleoplan.com/2011/03-30/why-no-grains-and-legumes/
http://simplehomemade.net/how-a-simple-diet-change-cured-infant-eczema/
@ Everyone: Please help add better citations for this article Laoseb97 ( talk) 17:46, 14 May 2013 (UTC)
@ Triougd: Thanks for replying and for your links you recommended to me.
I have a few clarifications and queries to make;
Laoseb97 ( talk) 19:17, 15 May 2013 (UTC)
Thank you for the links again - I have read them.
I understand the importance of sources in medical articles and I am sorry that my edits were substandard (in terms of what you said).
I think you said something about "alternative medicine" - I like the name (joke). Seriously though, In view of all that we have discussed , I am now contemplating making a new page called "Lectin hypothesis" as an alternative medicine stub-thing - I will take what i said on this article, on there and leave it as a hypothesis until somebody finds a black and white, peer reviewed, reliable source that supports it. Then I will collapse the page into "Atopic Dermatitis" . Meanwhile you could then revert (I don't know how to revert) the page, to your favorite archived version. Would you be in favor of that? Also any advice/ cautions would be appreciated.
I haven't been able to track down any credible source on it at all. I care about finding out exactly which hypothesis is the correct one, not whether or not that one is - Thanks for trying anyway.
Laoseb97 (
talk) 18:59, 16 May 2013 (UTC)
Oh, ok.
Ok.
In the light of your advice, I not going to make the new page (I know It is far more advanced than current sources suggest ( It counts as OR). I am better off not writing it on Wikipedia. Ill try and find some where else to post it- I might serve Better as Original research.
Thanks.
Laoseb97 (
talk) 18:38, 17 May 2013 (UTC)
I read this page out of interest after a patient decided they were an expert on Eczema after reading this Wikipedia article. I found a lot of factual errors in the article no doubt contributing to the widespread misconceptions about the causes of eczema.
Perhaps the editors for this page should have a thorough read of: http://dermnetnz.org/dermatitis/atopic-causes.html (and associated pages) which presents a more accurate view of the causes of eczema. It is written and edited by expert dermatologists. —Preceding unsigned comment added by 121.98.223.127 ( talk) 11:42, 20 January 2011 (UTC)
Completely agree with you. To read about dietary changes as treatment of AD means to be out of time. The main cause of AD is mutation of filaggrin which is present in about half cases, but the pathogenesis is complex. Vorticus ( talk) 22:04, 1 May 2016 (UTC)
Removing the nonsense about psyche and emotions barring a scholarly cite beyond Sontag, who was talking about popular culture reacting to disease, and not disease reacting to popular culture.
I don't know what you removed, but stress, including by extension emotionally induced stress, plays a major role in aggravating, and even causing (according to some) atopic dermatitis. Ken K. Smith (a.k.a. Thin Smek) ( talk) 16:33, 19 December 2018 (UTC)
also, it is NOT the same as a candida infection... if there is a relationship, then the previous author needs to provide a scholarly citation See: http://www.niams.nih.gov/hi/topics/dermatitis/
"neurodermatitis" should definitely be subsumed by "atopic dermatitis". AFAIK the latter (or equivalently, "atopic eczema") is now the preferred term.
References
1. regarding the merge with atopy: not a good idea, IMO, since atopic eczema is not the same thing as atopy, and the main eczema entry needs to be able to point to entries on each type.
2. regarding the merge with neurodermatitis: I argue against. There is some confusion on this issue, since in central Europe atopic eczema seems to be referred to -- some of the time -- as disseminated neurodermatitis. In the English speaking countries (and others?), however, neurodermatitis (or localized neurodermatitis) refers to lichen simplex chronicus and prurigo nodularis, eczemas either self-inflicted or of unknown etiology, but quite distinct from atopic dermatitis.
I think the entry on neurodermatitis should be returned to the original lichen simplex chronicus that has been overwritten with atopic stuff. V.B. 05:06, 9 October 2006 (UTC)V.B.
do not merge with atopy, they are distinct. -- Coroebus 19:21, 30 October 2006 (UTC)
Dont merge with atopy because as already mentioned atopy is a immune state rather than a disease in its self. Also the current trend in research is to actually group it with other inflammatory diseases such as crohns disease and leprosy, this is because of research into the role of barrier function in these diseases. Moreover as already mentioned atopy is defined as over production of IgE, well in 20-30% of cases of AD there is no IgE overproduction.
If you look up this entry on German Wiki, you will find that the neurodermitis term is the old one that is being superceded. However, it seems in common usage still. 170.215.67.24 05:26, 9 October 2006 (UTC)V.B.
I created a disambiguation page in reference to neurodermatitis, directing folks to either lichen/prurigo, or to atopic eczema. 170.215.67.24 22:53, 14 October 2006 (UTC)V.B.
"Although many people are intimidated by the term 'steroids,' their proper use can result in atopic dermatitis being brought under control."
This statement is not NPOV, and tends towards the irresponsible. Yes, strong steroids will superficially "cure" most skin problems. But there are also serious risks of systemic side-effects. It is important to use these drugs with care, and only use the minimum necessary, for a minimum time, to get the needed results.
"Alternative medicines may (illegally) contain very strong steroids"
Sure, they may. But most alternative medicines for eczema probably have no steroids. For example, GLA (
gamma-linolenic acid) a fatty acid found in evening primrose oil, black currant oil and
borage, is not a steriod. -
69.87.204.151 23:48, 2 March 2007 (UTC)
{{
cite journal}}
: CS1 maint: multiple names: authors list (
link)){{
cite journal}}
: Unknown parameter |month=
ignored (
help). Also same reasons for withdrawal in cyclical pre-menstrual breast discomfort in women.
[1])
{{
cite journal}}
: CS1 maint: multiple names: authors list (
link) concludes that "Dietary GLA-supplementation could not prevent AD"{{
cite journal}}
: CS1 maint: multiple names: authors list (
link) - concluded that " the overall response to borage oil did not reach statistical significance" and I note the study design description that: "Use of topical diflucortolone-21-valerate cream was allowed as rescue medication,".{{
cite journal}}
: Unknown parameter |month=
ignored (
help) - "Conclusion gamma linolenic acid is not beneficial in atopic dermatitis"The main short term side effects of using overly strong topical steroid are well-documented, because they can be extremely nasty. Using topical steroid over the long term (decades) causes permanently and drastically: thinned skin, reduced cortisone production, reduced sensitively to cortisone, increased inflammation, breakdown of skin due to collagen loss and replacement inhibition, and higher risk of cancer. However, the strength of steroid used is proportional to the severity of these long term side effects, using very weak steroid should have little effect, whereas very strong steroid may bring this effects forwards several years.
So a doctor will normally try to use the least strength for the shortest time, and promote alternative solutions such as avoiding irritants and moisturising x amount of times a day in order to reduce the need for (strong) steroids. There is a benefit versus risk logic used for deciding what strength to use, and when.
The fear of using too much steroid is quite rational to a degree, but perhaps aggravated by learning how certain sport competitions were won by steroid enhanced cheaters who then experienced extreme medical conditions. Also the strong psychological correlation between cheat and bad can be more like cheat equals abominable when it comes to one's favourite sports. Ken K. Smith (a.k.a. Thin Smek) ( talk) 17:09, 19 December 2018 (UTC)
Tagging User:Davidruben. Ken K. Smith (a.k.a. Thin Smek) ( talk) 17:19, 17 January 2019 (UTC)
NEJM review http://content.nejm.org/cgi/content/short/358/14/1483 JFW | T@lk 14:43, 6 April 2008 (UTC)
The umbrella term for inflammatory skin reactions is dermatitis, subdivisions are for example contact dermatitis and eczema. Eczema is further subdivided into atopic eczema and non-atopic eczema (depending on IgE levels)
Historically eczema, neurodermitis (neurodermatitis in Engl.) and atopic eczema were used as synonyms. Therefore the article on neurodermatitis should be deleted. A few lines in the atopic eczema article should suffice.
Johansson SG. Revised, global nomenclature for allergy. Unambiguous terms create clarity and prevent misunderstandings. Lakartidningen.2006;103:379-83. (in Swedish) Haddendaddendoedenda ( talk) 20:25, 15 February 2009 (UTC)
There is a journal article linked from the Wiki page on Dental amalgam controversy which concerns "The Beneficial Effect of Amalgam Replacement on Health in Patients with Autoimmunity". Article here. Atopic eczema is discussed as one of the disorders that can be affected (albeit, it is the one with the "lowest rate" of improvement). Asat ( talk) 20:57, 16 November 2009 (UTC)
Amalgam fillings have recently been banned in New Zealand, where I live, because it's now considered hazardous. Before that, it was considered perfectly healthy. Ken K. Smith (a.k.a. Thin Smek) ( talk) 16:03, 19 December 2018 (UTC)
Tagging User:Asat. Ken K. Smith (a.k.a. Thin Smek) ( talk) 17:20, 17 January 2019 (UTC)
We have this paper but it is not a review Rapaport, MJ (2003 May-Jun). "Corticosteroid addiction and withdrawal in the atopic: the red burning skin syndrome". Clinics in dermatology. 21 (3): 201–14.
PMID
12781438. {{
cite journal}}
: Check date values in: |date=
(
help); Unknown parameter |coauthors=
ignored (|author=
suggested) (
help)
Doc James (
talk ·
contribs ·
email) 05:17, 9 August 2011 (UTC)
What do you mean, "it's not a review?" — Preceding
unsigned comment added by
98.102.223.174 (
talk) 21:30, 8 January 2013 (UTC)
Bad reference: 16: "^ a b c . pp. 52–56. doi:10.2340/00015555-0565." ? The doi link goes to a DOI Not Found page.
Not-referenced: The first paragraph of Prevention -> Diet is not cited: "Originally controversial, the association of food allergy with atopic dermatitis has now been clearly demonstrated. Many common food allergens can trigger an allergic reaction: such as milk, nuts, cheese, tomatoes, wheat, yeast, soy, and corn. Many of these allergens are common ingredients in grocery store products (especially corn syrup, which is a sugar substitute). Specialty health food stores often carry products that do not contain common allergens."
I would like to see citations for each of those food items listed relative to atopic dermatitis. Thanks anyone working on this. — Preceding unsigned comment added by 75.97.112.151 ( talk) 14:10, 26 August 2011 (UTC)
"To combat the severe dryness associated with atopic dermatitis, a high-quality, dermatologist-approved moisturizer should be used daily." I'm not sure what the source for this sentence is. I used to use high-quality, dermatologist-approved moisturizer. After a while I decided it was pretty expensive and tried a form of petroleum jelly (similar ingredients) from sort-of the Dutch equivalent of the dollar store (actually just a store with cheap goods, not everything the same price). Anyway, this stuff is about 10 times as cheap and comparable to the "high-quality, dermatologist-approved moisturizer", at least for me. So I'd like to know the source for this sentence. W3ird N3rd ( talk) 04:11, 2 May 2012 (UTC)
Dairy/milk does contain more than just lectins. I think it is a mistake to reduce dairy/milk to lectins, there are other substances in milk (e.g. proteins like lactose, casein, albumin, immunogloblin) that can cause problems. There should be IMHO a dairy section. Tony Mach ( talk) 05:08, 13 May 2013 (UTC)
Currently the lack of vitamins is not described as a possible reason for atopic dermatitis, although there is indication that it plays a role:
References
I looked into this page because I had a sudden attack of this condition several days ago. My arm looked exactly like this picture. The rash appeared in half a minute (!) However, I am 35 and never had food allergies. This attack was seemingly caused by an antibiotic which was prescribed to me (I never took it before). My mother gave me hydrocortysone which worked immediately. But my arm was badly scarred after it, and by now there are still slight traces of scars. The article speaks of the condition as of chronic, but my case was apparently acute. And it says nothing of reaction to antibiotics. 93.80.113.253 ( talk) 14:52, 7 February 2015 (UTC)
"Things that commonly make it worse include wool clothing, soaps" - does this refer to Soap or Detergent? Most things labelled 'soap' in a supermarket are not traditional soap but contain detergents such as Sodium laureth sulfate, which is indeed a known irritant (as mentioned on its page). -- Melarish ( talk) 17:37, 8 November 2015 (UTC)
doi:10.1016/S0140-6736(15)00149-X JFW | T@lk 13:12, 11 March 2016 (UTC)
The following content are from evidence based management practice, unfortunately everything isn't referenced. Those who understand wikipedia rules do help to salvage the following. Thank you.
The advantage of the emollients is that it creates an artificial skin barrier to the impaired stratum corneum and retains hydration of the epidermis; when the water component evaporates, it cools the skin, this tends to decrease the blood supply to the skin and to lessen the release of inflammatory mediators, thus relieves the itch. The main function of emollients is possible prevention of aggravating factors of eczema.
especially microbes that have been associated with the following: Th1 type immunity, generation of TGF-, which suppresses Th2 responses, and induction of oral tolerance and IgA production, an essential component of mucosal immune defence.
In a study of mothers who have had at least one first-degree relative (or partner) with atopic disease (eczema, rhinitis, or asthma), the mother was given lactobacillus GG prenatally and their infants were given it postnatally for 6 months. At the age of 2 years in those receiving lactobacillus GG, the incidence of atopic eczema was 23% vs. 46% in controls, a highly significant result. It has recently been shown that this benefit is maintained at 4 years followup. [1] [2]
Corticosteroids have a strong anti-inflammatory action and this is the reason why they are so effective in eczema. The cellular effects are due to the binding of the glucocorticosteroids (GCS) to the cytosolic GCS receptor in nucleated cells. Since most cells have these receptors, the effects of the GCS are multiple. Once the steroids have bound to the receptor, there is conformational change in the GCS receptor complex; which moves to the nucleus. The GCS complex now binds to segments of DNA cell glucocorticoid-responsive elements. As a result, certain parts of the genome are affected, leading to increased or decreased transcription, with resulting increased or decreased cytokine production. GCS will also bind to NF-kB, which has been shown to be a regulator for many cytokines and cell adhesion molecules. Binding of GCS to NF-kB will switch off cytokine production, particularly of those cytokines concerned with T-cell-mediated inflammation. [3] [4] The loss of existing collagen and inhibition of new collagen formation and making the skin thinner is the main side-effect of topical steroids.
ciclosporin (risk factors includes nephrotoxic & carcinogenic), methotrexate, interferon gamma-1b, mycophenolate mofetil (risk factors include bone marrow suppression and the risks of malignancy)
Topical or systemic triazole antifungal preparations are also used appropriate for combating Pityrosporum orbiculare.
References
AFP
was invoked but never defined (see the
help page).MSR
was invoked but never defined (see the
help page).I noticed much better pictures on google images search for this Topic (actually, for Atopic Eczema itself). Photos showing dime- to quarter-sized red disks with several small whitish or yellowish bumps in the middle. Someone I know has a small outbreak, hence my interest. How does a main, single photo usually get swapped out on wikipedia? Ok to link to or display in an article 2 or more photos in wikimedia? Thank you all for your time. Vid2vid ( talk) 07:37, 24 November 2018 (UTC)
Will atopic dermatitis stay on your forever? 2405:ACC0:1102:B33A:3D00:B98E:7B49:554B ( talk) 10:33, 3 March 2023 (UTC)