The contents of the Anti-anxiety medication page were merged into Anxiolytic on September 16 2022. For the contribution history and old versions of the redirected page, please see its history; for the discussion at that location, see its talk page. |
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Should it be included here? It is approved for use in GAD in the European Union PablitoRun ( talk) 21:11, 25 May 2010 (UTC)
SSRIs are commonly prescribed for anxiety. Are they considered anxiolytics? Other than St John's Wort they aren't really mentioned in the article. -- Galaxiaad 21:22, 30 July 2005 (UTC)
Antidepressants such as SSRIs and tricyclic antidepressants are anxiolytic. Without being rude does anyone here actually know what the word anxiolytic means? Anxiolytic is a drug which relieves anxiety. It does not matter whether it takes a week for an SSRI to become effective, it is still an anxiolytic. The effectiveness of SSRIs is controversial in some circles but it is still classed as an anxiolytic because,,,, it is classed as having anxiolytic properties.-- Literaturegeek | T@1k? 18:24, 18 December 2008 (UTC)
Agree that SSRIs should be mentioned. Would like to avoid a discussion about the definition of the term 'anxiolytic', but I will add a section mentioning the anxiolytic properties of SSRIs. I hope this is an acceptable solution. O.mangold ( talk) 14:37, 3 August 2010 (UTC)
I would not consider beta blockers 'anxiolytic' by definition as they work solely on somatic symptoms. Have amended article but could poss. take out.
Some of the information on this page appears to be copied from http://www.absoluteastronomy.com/ref/anxiolytic and has been removed by me. This leaves some 'gaps' in the article, there are several other sentences that have been modified by other posters I've kept in. To be honest, I think this needs a complete rewrite - the structure was based on the material taken from the webpage and it's not now in any real order. That's why I added the cleanup tag. Berry 18:57, 25 April 2006
I have spent some time rewriting this page. Some things to remember for future editors: anxiolytics are agents used to treat the symptoms of anxiety - not an underlying anxiety pathology such as Generalized Anxiety Disorder. A lot of medications seem to have crept into this article that are not anxiolytics (such as neuroleptics). I've weeded them out. Ifnord 20:44, 24 July 2006 (UTC)
Could someone please add some information about the non-benzodiazepine anxiolytic etifoxine. It seems Stresam, a popular drug particularly in France for treating anxiety, makes use of this. Someone I know was on it, so I'm eager to find out more, but there doesn't seem to be info on Wikipedia yet. —The preceding unsigned comment was added by Steve Kroon ( talk • contribs) 06:54, 26 March 2007 (UTC).
Opiates were mentioned which while definitely having an instant effect on anxiety are also a drug class all to themselves. (( Perhaps a warning about the extreme addictiveness of opiate drugs (from the relatively safe synthetic codine to definitely not safe 'recreational' class A drugs) would be insulting everyone's intelligence. ))
Etifoxine appears to have effects very similar to benzodiazapines, including having a molecular structure that includes a benzoxazine group - I can't determine if it is significantly different - it appears to be a GABA enhancer which is what benzos are.
There are many substances that have secondary anxiolytic effects and are used to treat GAD and panic symptoms. Several tricyclic antidepressants (eg doxepin) and the non-tricyclic (and extremely unusual) mirtazapine (all by virtue of having antihistamine effects) and most antipsychotic medications have major sedative side effects and they are often prescribed as if they were anxiolyics, usually given in smaller doses than is recommended for their primary use. Both of these classes of drug tend to loose their beneficial side effects after long term use.
There are several other drugs which have sedative and anxiolytic properties as side effects (one should not confuse sedation with anxiolytic properties as a patient may be quite physically sedated but still experience mental panic or stress - a problem with using antipsychotics for their sedative properties). (( a drug for treating some kinds of parethesia is indicated for panic attacks but I can't remember what it is called )) Even if they belong to another official class of drug, they may be worth a mention as drugs sometimes used in conjunction with more traditional anxiolytic medications, ie the anticonvulsant carbamazepine. Carbamazepine has some popularity as an assistant to antidepressants and anxiolytics.
I don't know what the official status of alcohol is (apart from being a general menace to the community) but, as a drug (ethyl as opposed to cleaning fluid), it is very non specific and prone to paradoxical effects vs being a strong CNS depressant - it can cause rage and mania as well as worsening depression. Also it is rather addictive in some individuals, to state the obvious. But, non-the-less, it acts instantly and often has strong anti-anxiety effects. It's ability to consistently reduce social phobia is well known by any 'social drinker'.
Marijuana also suffers from paradoxical effects vs being a CNS depressant, including causing panic attacks and paranoia. Rage, mood swings and violent behaviour are not known effects, though intoxication and, rarely, psychotic episodes are a problem. I suggest the reference to Marijuana remain as it is for now, though, as always, some citations would be useful (hint hint).
I'll leave it to someone with actual medical training (hehe) to decide for or against additions to this article re medications that touch anxiolytics while not strictly being a part of the classification. —Preceding unsigned comment added by Jp adelaide ( talk • contribs) 15:02, 31 October 2007 (UTC)
Marijuana is in no way an anxiolytic. It actually increases anxiety in a huge number of people who use it. —Preceding unsigned comment added by 76.109.190.197 ( talk) 01:09, 21 February 2008 (UTC)
I think that the section on marijuana should be edited. Marijuana does not have antipsychotic or anxiolytic effects, one of the chemicals contained in it has that effect. The reference is for CBD not marijuana, and the opening line of that reference states "A high dose of ∆9-tetrahydrocannabinol, the main Cannabis sativa (cannabis) component, induces anxiety and psychotic-like symptoms in healthy volunteers." So it would be good to clarify that. Essent ( talk) 18:51, 28 February 2008 (UTC)
marijuana can cause anxiety as well, this should definitely mentioned. —Preceding unsigned comment added by 86.154.155.214 ( talk) 17:26, 26 March 2008 (UTC)
Why is this drug not mentioned? TimL ( talk) 13:36, 17 May 2008 (UTC)
Good point, it should be listed. I just added it to the article with a citation.-- Literaturegeek | T@1k? 14:19, 17 May 2008 (UTC)
http://en.wikipedia.org/wiki/Coriander links to this page but is not listed under the Herbal section, if someone could edit that in properly. I don't know how. 64.105.35.105 ( talk) 09:39, 22 May 2008 (UTC) (Just wandering through)ki Likewise, the Chamomile page links to this, but is not included in the list of herbs. Can anyone support and write on Chamomile as an anxiolytic? The claim on the Chamomile page is it has this effect on rodents. IT looks like only 2-3 herbs currently listed are supported by adequate research. Does anyone know a source for the efficacy of Chamomile as an anxiolytic?
"Benzodiazepines are prescribed for short-term relief of severe and disabling anxiety"
This seems a bit of asweeping statement - benzos arnt always prescribed for short term use only, and they are sometimes used for moderate as opposed to severe, disabeling anxiety
121.209.52.159 ( talk) 01:55, 30 March 2010 (UTC) Jonathan
Really? This article http://www.ncbi.nlm.nih.gov/pubmed/12652886 on lateriflora says valerian, kava-kava, St. John's Wort, passion flower, and hops have all been shown effective in double blind controlled studies. — Preceding unsigned comment added by 96.224.73.39 ( talk) 19:27, 17 July 2011 (UTC)
alpha-2 adrenoreceptor agonists such as clonidine and detomidine are indicated as sedatives and can produce a significant anxiolytic effect by preventing the release of adrenaline in both the CNS and PNS, reliving both the psychological and physiological symptoms of anxiety, they are sometimes used clinically for treating anxiety disorders with positive evidence from RCT's also. Would be nice if someone could add this class of drugs to the list sometime. 151.225.64.244 ( talk) 23:02, 30 September 2014 (UTC)
Though no doctor would prescribe them for anxiety they certainly have anxiolytic properties.
http://www.ncbi.nlm.nih.gov/pubmed/25544740 — Preceding unsigned comment added by 78.146.5.156 ( talk) 08:03, 17 March 2015 (UTC)
Anti epileptic medications (lamictal, Tegretol, topamax, pregabalin, etc) have been used for anxiety in doses lower than the anti-convulsant doses. When I've tried creating a category for them it got deleted.
I don't want to go through the trouble of creating the category again if it is just going to be deleted, so why is it deleted? If anything, anti-convulsants are a more mainstream therapy for anxiety than opioids, and opioids have their own category.
Hello,
You should look into Etifoxine (Stresam), it already prescribed in France, Russia and other countries.
You could also talk about cannabinoids, especially CBD which is well known (CB1 modulator and 5HT1a agonist ...). Also CB receptors modulators like Kava.
You could also talk about potent plant extracts like Ashwagandha (reduces cortisol, works on 5HT2a...), Lemon balm (GABA transaminase inhibitor...), valerian root, lavender, ... Showing all different mechanisms.
You could also talk about amino acids like L-theanine (glutamic acid blocker, AMPA antagonist, NMDA agonist...), N-acetyl Cysteine, glycine, taurine, ... Also the mineral magnesium and especially magnesium glycinate.
You did not mention picamilon, which is simply GABA + Niacin ir order to make it able to pass through the blood brain barrier.
Thanks !
Its placement and availability had seemed to be on the rise, but now, rather suddenly it seems, it has just as simply and swiftly 'disappeared'...?
173.72.129.248 ( talk) 04:40, 26 May 2022 (UTC)
I propose merging anti-anxiety medication into anxiolytic. I think the content in anti-anxiety medication, which includes more history and context, can be easily added to anxiolytic, which currently is more focused on discussing specific medications. I don't anticipate article size or weighting problems. I'm rather new around here, and I'm not an expert on anxiety meds, so please let me know if I'm totally off base. Thanks! Crunchydillpickle ( talk) 15:13, 2 June 2022 (UTC)
Okay, I merged Anti-anxiety medication into Anxiolytic. There is a lot of redundancy, or at least each drug gets talked about in multiple sections. I am wondering about the structure. Would it make sense to simply have a section for each medication (or type?), with all information about that medication in that section? As it is, things are a bit of a mess. Thoughts? Doctormatt ( talk) 23:22, 16 September 2022 (UTC)
Please note that an article was created attempting but failing to duplicate content from this article. I have since redirected it here. TheTechnician27 (Talk page) 23:59, 11 August 2023 (UTC)
The contents of the Anti-anxiety medication page were merged into Anxiolytic on September 16 2022. For the contribution history and old versions of the redirected page, please see its history; for the discussion at that location, see its talk page. |
This is the
talk page for discussing improvements to the
Anxiolytic article. This is not a forum for general discussion of the article's subject. |
Article policies
|
Find medical sources: Source guidelines · PubMed · Cochrane · DOAJ · Gale · OpenMD · ScienceDirect · Springer · Trip · Wiley · TWL |
This
level-5 vital article is rated C-class on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: |
||||||||||||||||||||||||||||||||||
|
Should it be included here? It is approved for use in GAD in the European Union PablitoRun ( talk) 21:11, 25 May 2010 (UTC)
SSRIs are commonly prescribed for anxiety. Are they considered anxiolytics? Other than St John's Wort they aren't really mentioned in the article. -- Galaxiaad 21:22, 30 July 2005 (UTC)
Antidepressants such as SSRIs and tricyclic antidepressants are anxiolytic. Without being rude does anyone here actually know what the word anxiolytic means? Anxiolytic is a drug which relieves anxiety. It does not matter whether it takes a week for an SSRI to become effective, it is still an anxiolytic. The effectiveness of SSRIs is controversial in some circles but it is still classed as an anxiolytic because,,,, it is classed as having anxiolytic properties.-- Literaturegeek | T@1k? 18:24, 18 December 2008 (UTC)
Agree that SSRIs should be mentioned. Would like to avoid a discussion about the definition of the term 'anxiolytic', but I will add a section mentioning the anxiolytic properties of SSRIs. I hope this is an acceptable solution. O.mangold ( talk) 14:37, 3 August 2010 (UTC)
I would not consider beta blockers 'anxiolytic' by definition as they work solely on somatic symptoms. Have amended article but could poss. take out.
Some of the information on this page appears to be copied from http://www.absoluteastronomy.com/ref/anxiolytic and has been removed by me. This leaves some 'gaps' in the article, there are several other sentences that have been modified by other posters I've kept in. To be honest, I think this needs a complete rewrite - the structure was based on the material taken from the webpage and it's not now in any real order. That's why I added the cleanup tag. Berry 18:57, 25 April 2006
I have spent some time rewriting this page. Some things to remember for future editors: anxiolytics are agents used to treat the symptoms of anxiety - not an underlying anxiety pathology such as Generalized Anxiety Disorder. A lot of medications seem to have crept into this article that are not anxiolytics (such as neuroleptics). I've weeded them out. Ifnord 20:44, 24 July 2006 (UTC)
Could someone please add some information about the non-benzodiazepine anxiolytic etifoxine. It seems Stresam, a popular drug particularly in France for treating anxiety, makes use of this. Someone I know was on it, so I'm eager to find out more, but there doesn't seem to be info on Wikipedia yet. —The preceding unsigned comment was added by Steve Kroon ( talk • contribs) 06:54, 26 March 2007 (UTC).
Opiates were mentioned which while definitely having an instant effect on anxiety are also a drug class all to themselves. (( Perhaps a warning about the extreme addictiveness of opiate drugs (from the relatively safe synthetic codine to definitely not safe 'recreational' class A drugs) would be insulting everyone's intelligence. ))
Etifoxine appears to have effects very similar to benzodiazapines, including having a molecular structure that includes a benzoxazine group - I can't determine if it is significantly different - it appears to be a GABA enhancer which is what benzos are.
There are many substances that have secondary anxiolytic effects and are used to treat GAD and panic symptoms. Several tricyclic antidepressants (eg doxepin) and the non-tricyclic (and extremely unusual) mirtazapine (all by virtue of having antihistamine effects) and most antipsychotic medications have major sedative side effects and they are often prescribed as if they were anxiolyics, usually given in smaller doses than is recommended for their primary use. Both of these classes of drug tend to loose their beneficial side effects after long term use.
There are several other drugs which have sedative and anxiolytic properties as side effects (one should not confuse sedation with anxiolytic properties as a patient may be quite physically sedated but still experience mental panic or stress - a problem with using antipsychotics for their sedative properties). (( a drug for treating some kinds of parethesia is indicated for panic attacks but I can't remember what it is called )) Even if they belong to another official class of drug, they may be worth a mention as drugs sometimes used in conjunction with more traditional anxiolytic medications, ie the anticonvulsant carbamazepine. Carbamazepine has some popularity as an assistant to antidepressants and anxiolytics.
I don't know what the official status of alcohol is (apart from being a general menace to the community) but, as a drug (ethyl as opposed to cleaning fluid), it is very non specific and prone to paradoxical effects vs being a strong CNS depressant - it can cause rage and mania as well as worsening depression. Also it is rather addictive in some individuals, to state the obvious. But, non-the-less, it acts instantly and often has strong anti-anxiety effects. It's ability to consistently reduce social phobia is well known by any 'social drinker'.
Marijuana also suffers from paradoxical effects vs being a CNS depressant, including causing panic attacks and paranoia. Rage, mood swings and violent behaviour are not known effects, though intoxication and, rarely, psychotic episodes are a problem. I suggest the reference to Marijuana remain as it is for now, though, as always, some citations would be useful (hint hint).
I'll leave it to someone with actual medical training (hehe) to decide for or against additions to this article re medications that touch anxiolytics while not strictly being a part of the classification. —Preceding unsigned comment added by Jp adelaide ( talk • contribs) 15:02, 31 October 2007 (UTC)
Marijuana is in no way an anxiolytic. It actually increases anxiety in a huge number of people who use it. —Preceding unsigned comment added by 76.109.190.197 ( talk) 01:09, 21 February 2008 (UTC)
I think that the section on marijuana should be edited. Marijuana does not have antipsychotic or anxiolytic effects, one of the chemicals contained in it has that effect. The reference is for CBD not marijuana, and the opening line of that reference states "A high dose of ∆9-tetrahydrocannabinol, the main Cannabis sativa (cannabis) component, induces anxiety and psychotic-like symptoms in healthy volunteers." So it would be good to clarify that. Essent ( talk) 18:51, 28 February 2008 (UTC)
marijuana can cause anxiety as well, this should definitely mentioned. —Preceding unsigned comment added by 86.154.155.214 ( talk) 17:26, 26 March 2008 (UTC)
Why is this drug not mentioned? TimL ( talk) 13:36, 17 May 2008 (UTC)
Good point, it should be listed. I just added it to the article with a citation.-- Literaturegeek | T@1k? 14:19, 17 May 2008 (UTC)
http://en.wikipedia.org/wiki/Coriander links to this page but is not listed under the Herbal section, if someone could edit that in properly. I don't know how. 64.105.35.105 ( talk) 09:39, 22 May 2008 (UTC) (Just wandering through)ki Likewise, the Chamomile page links to this, but is not included in the list of herbs. Can anyone support and write on Chamomile as an anxiolytic? The claim on the Chamomile page is it has this effect on rodents. IT looks like only 2-3 herbs currently listed are supported by adequate research. Does anyone know a source for the efficacy of Chamomile as an anxiolytic?
"Benzodiazepines are prescribed for short-term relief of severe and disabling anxiety"
This seems a bit of asweeping statement - benzos arnt always prescribed for short term use only, and they are sometimes used for moderate as opposed to severe, disabeling anxiety
121.209.52.159 ( talk) 01:55, 30 March 2010 (UTC) Jonathan
Really? This article http://www.ncbi.nlm.nih.gov/pubmed/12652886 on lateriflora says valerian, kava-kava, St. John's Wort, passion flower, and hops have all been shown effective in double blind controlled studies. — Preceding unsigned comment added by 96.224.73.39 ( talk) 19:27, 17 July 2011 (UTC)
alpha-2 adrenoreceptor agonists such as clonidine and detomidine are indicated as sedatives and can produce a significant anxiolytic effect by preventing the release of adrenaline in both the CNS and PNS, reliving both the psychological and physiological symptoms of anxiety, they are sometimes used clinically for treating anxiety disorders with positive evidence from RCT's also. Would be nice if someone could add this class of drugs to the list sometime. 151.225.64.244 ( talk) 23:02, 30 September 2014 (UTC)
Though no doctor would prescribe them for anxiety they certainly have anxiolytic properties.
http://www.ncbi.nlm.nih.gov/pubmed/25544740 — Preceding unsigned comment added by 78.146.5.156 ( talk) 08:03, 17 March 2015 (UTC)
Anti epileptic medications (lamictal, Tegretol, topamax, pregabalin, etc) have been used for anxiety in doses lower than the anti-convulsant doses. When I've tried creating a category for them it got deleted.
I don't want to go through the trouble of creating the category again if it is just going to be deleted, so why is it deleted? If anything, anti-convulsants are a more mainstream therapy for anxiety than opioids, and opioids have their own category.
Hello,
You should look into Etifoxine (Stresam), it already prescribed in France, Russia and other countries.
You could also talk about cannabinoids, especially CBD which is well known (CB1 modulator and 5HT1a agonist ...). Also CB receptors modulators like Kava.
You could also talk about potent plant extracts like Ashwagandha (reduces cortisol, works on 5HT2a...), Lemon balm (GABA transaminase inhibitor...), valerian root, lavender, ... Showing all different mechanisms.
You could also talk about amino acids like L-theanine (glutamic acid blocker, AMPA antagonist, NMDA agonist...), N-acetyl Cysteine, glycine, taurine, ... Also the mineral magnesium and especially magnesium glycinate.
You did not mention picamilon, which is simply GABA + Niacin ir order to make it able to pass through the blood brain barrier.
Thanks !
Its placement and availability had seemed to be on the rise, but now, rather suddenly it seems, it has just as simply and swiftly 'disappeared'...?
173.72.129.248 ( talk) 04:40, 26 May 2022 (UTC)
I propose merging anti-anxiety medication into anxiolytic. I think the content in anti-anxiety medication, which includes more history and context, can be easily added to anxiolytic, which currently is more focused on discussing specific medications. I don't anticipate article size or weighting problems. I'm rather new around here, and I'm not an expert on anxiety meds, so please let me know if I'm totally off base. Thanks! Crunchydillpickle ( talk) 15:13, 2 June 2022 (UTC)
Okay, I merged Anti-anxiety medication into Anxiolytic. There is a lot of redundancy, or at least each drug gets talked about in multiple sections. I am wondering about the structure. Would it make sense to simply have a section for each medication (or type?), with all information about that medication in that section? As it is, things are a bit of a mess. Thoughts? Doctormatt ( talk) 23:22, 16 September 2022 (UTC)
Please note that an article was created attempting but failing to duplicate content from this article. I have since redirected it here. TheTechnician27 (Talk page) 23:59, 11 August 2023 (UTC)