Ken Wolfe | |
---|---|
Born | Kenneth Henry Wolfe |
Alma mater | Trinity College Dublin (BA, PhD) |
Awards | EMBO Member (2010) [1] |
Scientific career | |
Fields |
Comparative genomics Yeast genetics Bioinformatics [2] |
Institutions |
University College Dublin Trinity College Dublin Indiana University Bloomington [3] |
Thesis | Rates of nucleotide substitution in higher plants and mammals (1990) |
Doctoral advisor | Paul M. Sharp [4] [5] [6] |
Other academic advisors | Jeffrey D. Palmer [7] |
Doctoral students | |
Website |
wolfe |
Kenneth Henry Wolfe FRS MRIA [11] [12] is an Irish geneticist and professor of genomic evolution at University College Dublin (UCD), Ireland. [13] [11] [14]
Wolfe was educated at Trinity College Dublin, where he was awarded Bachelor of Arts degree in genetics in 1986 [3] followed by a PhD in 1990 [6] for research investigating synonymous substitution in vascular plants and mammals supervised by Paul M. Sharp. [4] [5] [6] [15]
Wolfe's research focuses on comparative genomics, yeast genetics and bioinformatics. [2] [16] [17] Work in his laboratory investigates the evolution of eukaryotic genomes and chromosome organisation. [12] He is best known for his discovery that the genome of the yeast Saccharomyces cerevisiae underwent complete genome duplication about 100 million years ago, [18] an event that is now known to be the result of hybridization between two divergent species. [12] This finding reshaped our understanding both of yeast biology, and of mechanisms of genome evolution in eukaryotes. [12] His subsequent discoveries of similar ancient genome duplications (paleopolyploidy) [19] during human evolution, and in almost all families of flowering plants, led to the realisation that whole-genome duplication is widespread. [12] His group also studies the origin and evolution of mating systems in yeasts, and the process of mating-type switching in which one cell type can change into another by moving or replacing a section of chromosome. [12]
Wolfe was a postdoctoral researcher with Jeffrey D. Palmer [7] at Indiana University Bloomington before returning to Ireland in 1992 to establish his research group in the genetics department of Trinity College Dublin, [20] [3] where he remained for over 20 years. In 2013, he moved to University College Dublin's UCD School of Medicine and Conway Institute. [21] As of 2017 [update] his most highly cited peer reviewed papers [2] [14] [16] have been published in leading scientific journals including Nature, [18] [22] PNAS, [23] The Plant Cell, [19] [24] Genome Research [25] and Nature Reviews Genetics. [7]
Former doctoral students from the Wolfe lab include Mario A. Fares, [4] Aoife McLysaght, [4] [8] [9] Estelle Proux-Wéra [4] and Cathal Seoighe. [5] [10]
Wolfe was elected a Fellow of the Royal Society (FRS) in 2017, [12] a member of the Royal Irish Academy (MRIA) in 2000 [11] and a member of the European Molecular Biology Organization (EMBO) in 2010. [1] In 2011 he served as president of the Society for Molecular Biology and Evolution (smbe.org). [26]
"All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License." -- "Royal Society Terms, conditions and policies". Archived from the original on 11 November 2016. Retrieved 9 March 2016.
{{ cite web}}
: CS1 maint: bot: original URL status unknown ( link)
Ken Wolfe | |
---|---|
Born | Kenneth Henry Wolfe |
Alma mater | Trinity College Dublin (BA, PhD) |
Awards | EMBO Member (2010) [1] |
Scientific career | |
Fields |
Comparative genomics Yeast genetics Bioinformatics [2] |
Institutions |
University College Dublin Trinity College Dublin Indiana University Bloomington [3] |
Thesis | Rates of nucleotide substitution in higher plants and mammals (1990) |
Doctoral advisor | Paul M. Sharp [4] [5] [6] |
Other academic advisors | Jeffrey D. Palmer [7] |
Doctoral students | |
Website |
wolfe |
Kenneth Henry Wolfe FRS MRIA [11] [12] is an Irish geneticist and professor of genomic evolution at University College Dublin (UCD), Ireland. [13] [11] [14]
Wolfe was educated at Trinity College Dublin, where he was awarded Bachelor of Arts degree in genetics in 1986 [3] followed by a PhD in 1990 [6] for research investigating synonymous substitution in vascular plants and mammals supervised by Paul M. Sharp. [4] [5] [6] [15]
Wolfe's research focuses on comparative genomics, yeast genetics and bioinformatics. [2] [16] [17] Work in his laboratory investigates the evolution of eukaryotic genomes and chromosome organisation. [12] He is best known for his discovery that the genome of the yeast Saccharomyces cerevisiae underwent complete genome duplication about 100 million years ago, [18] an event that is now known to be the result of hybridization between two divergent species. [12] This finding reshaped our understanding both of yeast biology, and of mechanisms of genome evolution in eukaryotes. [12] His subsequent discoveries of similar ancient genome duplications (paleopolyploidy) [19] during human evolution, and in almost all families of flowering plants, led to the realisation that whole-genome duplication is widespread. [12] His group also studies the origin and evolution of mating systems in yeasts, and the process of mating-type switching in which one cell type can change into another by moving or replacing a section of chromosome. [12]
Wolfe was a postdoctoral researcher with Jeffrey D. Palmer [7] at Indiana University Bloomington before returning to Ireland in 1992 to establish his research group in the genetics department of Trinity College Dublin, [20] [3] where he remained for over 20 years. In 2013, he moved to University College Dublin's UCD School of Medicine and Conway Institute. [21] As of 2017 [update] his most highly cited peer reviewed papers [2] [14] [16] have been published in leading scientific journals including Nature, [18] [22] PNAS, [23] The Plant Cell, [19] [24] Genome Research [25] and Nature Reviews Genetics. [7]
Former doctoral students from the Wolfe lab include Mario A. Fares, [4] Aoife McLysaght, [4] [8] [9] Estelle Proux-Wéra [4] and Cathal Seoighe. [5] [10]
Wolfe was elected a Fellow of the Royal Society (FRS) in 2017, [12] a member of the Royal Irish Academy (MRIA) in 2000 [11] and a member of the European Molecular Biology Organization (EMBO) in 2010. [1] In 2011 he served as president of the Society for Molecular Biology and Evolution (smbe.org). [26]
"All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License." -- "Royal Society Terms, conditions and policies". Archived from the original on 11 November 2016. Retrieved 9 March 2016.
{{ cite web}}
: CS1 maint: bot: original URL status unknown ( link)